As the population of the U.S. ages and increases in life expectancy continue, the length of time between onset of disease and death may expand or contract. The economic consequences of such expansion or compression of morbidity could be significant. A research program is proposed which seeks to: 1) measure the health care resource use of older adults; 2) estimate the relationship of health care resource use to morbidity and disability in older adults; 3) model the impact that expansion or compression of morbidity would have on population-based expenditures for health care of older adults; 4) investigate and model the economic impact of interventions designed to prevent disease and disability in older adults. The candidate for this award has a research background and experience in: 1) health care economics and financing including measurement of the direct costs of illness in prospective observational studies, 2) multi- disciplinary research of health care interventions and 3) recent experience in evaluating the impact of diseases of older adults. The initial focus of this research program will be on cardiovascular disease in older adults, the leading cause of morbidity and mortality in this population. Methods of estimating and modeling health care resource in older adults with cardiovascular disease will subsequently be modified and applied to other significant diseases/conditions in older adults.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01AG000561-04
Application #
2048322
Study Section
Neuroscience, Behavior and Sociology of Aging Review Committee (NBSA)
Project Start
1992-08-14
Project End
1997-07-31
Budget Start
1995-08-15
Budget End
1996-07-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Dong, Hongxin; Yuede, Carla M; Coughlan, Carolyn et al. (2008) Effects of memantine on neuronal structure and conditioned fear in the Tg2576 mouse model of Alzheimer's disease. Neuropsychopharmacology 33:3226-36
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Danese, M D; Powe, N R; Sawin, C T et al. (1996) Screening for mild thyroid failure at the periodic health examination: a decision and cost-effectiveness analysis. JAMA 276:285-92
Davidoff, A J; Powe, N R (1996) The role of perspective in defining economic measures for the evaluation of medical technology. Int J Technol Assess Health Care 12:9-21
Powe, N R; Griffiths, R I (1995) The clinical-economic trial: promise, problems, and challenges. Control Clin Trials 16:377-94
Powe, N R (1994) Economic and cost-effectiveness investigations of radiologic practices. Radiology 192:11-8
Powe, N R; Moore, R D; Steinberg, E P (1993) Adverse reactions to contrast media: factors that determine the cost of treatment. AJR Am J Roentgenol 161:1089-95