The purpose of this K01 Mentored Research Scientist Development Award is to promote the candidate's development as an independent researcher in complementary and alternative medicine (CAM) with a focus on chronic disease management among underserved populations. Dr. Chao's long-term career goal is to bridge public health and CAM to improve quality of life among underserved populations living with chronic conditions, such as diabetes. Towards this end, the proposed mentored research for this K01 award is to design, implement, and evaluate an acupuncture group-based intervention to improve quality of life among underserved patients with painful diabetic neuropathy. To support this research and Dr. Chao's goal of independent CAM research, this K01 application includes formal, mentored training through coursework and tailored tutorials in clinical research methodologies, practice-based acupuncture research, diabetes management and quality of life among underserved populations, and responsible conduct of research. This training will be applied to research with two Specific Aims: (1) to develop a standardized acupuncture protocol for painful diabetic neuropathy through formal treatment manualization;and (2) to evaluate acceptability, feasibility, and preliminary efficacy of group acupuncture for painful diabetic neuropathy among underserved patients. The University of California, San Francisco is an ideal environment for the proposed training because it provides access to experts in both CAM and diabetes management among underserved populations and close affiliation with San Francisco General Hospital, an urban safety net hospital serving a low-income, ethnically diverse population. Completion of the proposed research and career development activities will inform the development of an R01 application and ensure Dr. Chao's ability to conduct independent research on CAM therapies to improve quality of life among underserved populations.

Public Health Relevance

Chronic pain is highly prevalent among people with diabetes and negatively impacts on quality of life, daily functioning, and ability to engage in self-management of disease. Given the limitations of standard pharmaceutical treatments for pain, alternative approaches to effective pain management are critically needed to improve quality of life, especially among vulnerable populations who are most at risk of suffering from diabetes and undertreated for pain. If the proposed aims are achieved, group acupuncture may provide a viable model for improving quality of life among underserved diabetes populations that can be implemented in safety net hospitals and other settings.

National Institute of Health (NIH)
National Center for Complementary & Alternative Medicine (NCCAM)
Research Scientist Development Award - Research & Training (K01)
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Special Emphasis Panel (ZAT1-PK (14))
Program Officer
Huntley, Kristen V
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University of California San Francisco
Internal Medicine/Medicine
Schools of Medicine
San Francisco
United States
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Liu, Rhianon; Chao, Maria T; Jostad-Laswell, Ariana et al. (2017) Does CenteringPregnancy Group Prenatal Care Affect the Birth Experience of Underserved Women? A Mixed Methods Analysis. J Immigr Minor Health 19:415-422
Duncan, Larissa G; Cohn, Michael A; Chao, Maria T et al. (2017) Benefits of preparing for childbirth with mindfulness training: a randomized controlled trial with active comparison. BMC Pregnancy Childbirth 17:140
Chang, Alexandra; Acquah, Joseph; Reddy, Sanjay et al. (2016) Acupuncture for the Management of Postdural Puncture Headache: A Case Report. Glob Adv Health Med 5:103-6
Wade, C; Wang, L; Zhao, W J et al. (2016) Acupuncture point injection treatment of primary dysmenorrhoea: a randomised, double blind, controlled study. BMJ Open 6:e008166
Liu, Rhianon; Chang, Alexandra; Reddy, Sanjay et al. (2016) Improving Patient-Centered Care: A Cross-Sectional Survey of Prior Use and Interest in Complementary and Integrative Health Approaches Among Hospitalized Oncology Patients. J Altern Complement Med 22:160-5
Chao, Maria T; Chang, Alexandra; Reddy, Sanjay et al. (2016) Adjunctive acupuncture for pain and symptom management in the inpatient setting: protocol for a pilot hybrid effectiveness-implementation study. J Integr Med 14:228-38
Chao, M T; Handley, M A; Quan, J et al. (2015) Disclosure of complementary health approaches among low income and racially diverse safety net patients with diabetes. Patient Educ Couns 98:1360-6
Chao, Maria T; Abercrombie, Priscilla D; Nakagawa, Sanae et al. (2015) Prevalence and use of complementary health approaches among women with chronic pelvic pain in a prospective cohort study. Pain Med 16:328-40
Chao, Maria T; Abercrombie, Priscilla D; Santana, Trilce et al. (2015) Applying the RE-AIM Framework to Evaluate Integrative Medicine Group Visits Among Diverse Women with Chronic Pelvic Pain. Pain Manag Nurs 16:920-9
Chao, Maria T; Wade, Christine M; Abercrombie, Priscilla D et al. (2014) An innovative acupuncture treatment for primary dysmenorrhea: a randomized, crossover pilot study. Altern Ther Health Med 20:49-56

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