This Mentored Research Scientist Development Award describes a training and research plan designed to qualify the candidate to design and conduct research on the prevention of smoking relapse during the postpartum period. Although many women quit smoking during pregnancy, approximately 70% will resume smoking within a year of giving birth. Because smoking during the postpartum period has negative effects on the health of both women and children, preventing postpartum relapses to smoking can have important public health benefits. To date, however, little is known about the causes or prevention of postpartum smoking. Changes in mood and increases in concerns about weight are common during the postpartum period, and these factors also have been related to women's smoking behavior. Thus, it is hypothesized that mood and weight concerns increase women's vulnerability to postpartum smoking relapse. ? ? To elucidate the effects of mood and weight concerns on postpartum smoking, the candidate proposes a research plan designed to: (1) assess factors theoretically related to postpartum smoking relapse; (2) develop a postpartum-specific relapse prevention program addressing factors found to relate to postpartum relapse; and (3) test the feasibility, acceptability and initial efficacy of this postpartum-specific relapse prevention program. This research plan is combined with a training plan designed to establish a strong knowledge base in the following areas: (1) the physiologic effects of nicotine and tobacco on women, (2) factors in the postpartum period that affect mood and weight, and (3) advanced longitudinal data analytic techniques. The background and skills developed during through this research and training plan will provide a cohesive framework for the candidate's future career as an independent investigator in the area of clinical research on approaches to women's smoking cessation.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01DA015396-05
Application #
7093583
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Grossman, Debra
Project Start
2002-09-30
Project End
2008-05-31
Budget Start
2006-06-01
Budget End
2008-05-31
Support Year
5
Fiscal Year
2006
Total Cost
$116,286
Indirect Cost
Name
University of Pittsburgh
Department
Psychiatry
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Slane, Jennifer D; Levine, Michele D (2015) Association of Restraint and Disinhibition to Gestational Weight Gain among Pregnant Former Smokers. Womens Health Issues 25:390-5
Emery, Rebecca L; Levine, Michele D; Cheng, Yu et al. (2015) Change in Body Weight Does Not Mediate the Relationship Between Exercise and Smoking Cessation Among Weight-Concerned Women Smokers. Nicotine Tob Res 17:1142-8
Levine, Michele D; Cheng, Yu; Marcus, Marsha D et al. (2012) Relapse to smoking and postpartum weight retention among women who quit smoking during pregnancy. Obesity (Silver Spring) 20:457-9
Levine, Michele D; Cheng, Yu; Kalarchian, Melissa A et al. (2012) Dietary intake after smoking cessation among weight-concerned women smokers. Psychol Addict Behav 26:969-73
Levine, Michele D; Perkins, Kenneth A; Kalarchian, Melissa A et al. (2010) Bupropion and cognitive behavioral therapy for weight-concerned women smokers. Arch Intern Med 170:543-50
Levine, Michele D; Marcus, Marsha D; Kalarchian, Melissa A et al. (2010) Weight concerns, mood, and postpartum smoking relapse. Am J Prev Med 39:345-51
Qin, Li; Weissfeld, Lisa A; Shen, Changyu et al. (2009) A Two-Latent-Class Model for Smoking Cessation Data with Informative Dropouts. Commun Stat Theory Methods 38:2604-2619
Ringham, Rebecca; Levine, Michele; Kalarchian, Melissa et al. (2008) Temperament, mood, dietary restraint, and bulimic symptomatology in college women. Eat Behav 9:336-42
Levine, Michele D; Marcus, Marsha D; Leon-Verdin, MaGuadalupe (2008) Similarities in affect, perceived stress, and weight concerns between Black and White women who quit smoking during pregnancy. Nicotine Tob Res 10:1543-8
Levine, Michele D (2008) Women's interest in treatment to stay abstinent from cigarettes postpartum. Womens Health Issues 18:381-6

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