? Economic evaluation of drug prevention programs and treatment interventions is critical to identify the most efficient use of scarce resources. While work in this area continues to grow, there is still a dearth of rigorous economic evaluations of such programs. This K01 Award would allow Dr. Jennifer Prah Ruger to advance her skills to conduct health economic and policy research on the efficiency of addiction services among vulnerable populations such as women, adolescents and members of minority groups to ultimately improve addiction services for these underserved populations.
The specific aims of this proposal are: (1) to acquire advanced knowledge of the epidemiology and etiology of substance use disorders; (2) to develop greater understanding of clinical approaches to the assessment and treatment of drug use disorders and associated comorbid conditions; (3) to enhance knowledge and skills pertaining specifically to the economic evaluation of addiction services; and (4) to obtain ongoing training in the responsible conduct of research. Dr. Prah Ruger's career development plan includes supervised study with Linda B. Cottler, Ph.D. in relation to epidemiological and substance abuse issues; with Arlene Rubin Stiffman, Ph.D. on issues related to substance abuse and mental health services for adolescents; and with Michael T. French, Ph.D. and Milton C. Weinstein, Ph.D. on the methods of economic evaluation, along with coursework, grand rounds, relevant seminar series, and professional meetings. Dr. Prah Ruger will use the knowledge and skills developed through these career development activities to conduct three research projects. The first project includes an assessment of the cost effectiveness of a smoking cessation program for low-income pregnant women (Dr. Weinstein). The second project evaluates the incremental cost-effectiveness and cost-utility analysis of a three-arm public health intervention to prevent HIV and STDs in at-risk, drug-using women (Drs. Cottler and Weinstein). The third project examines the costs of addiction and mental health services for reservation- and urban-based American Indian youth (Drs. Stiffman and French). The proposed plan will provide Dr. Prah Ruger with the training, mentoring, time and resources to develop the specific skills and knowledge that will allow her to lead independent research on the economic evaluation of addictive services. ? ? ? ?

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Scientist Development Award - Research & Training (K01)
Project #
Application #
Study Section
Special Emphasis Panel (ZDA1-KXA-N (39))
Program Officer
Duffy, Sarah Q
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Yale University
Public Health & Prev Medicine
Schools of Medicine
New Haven
United States
Zip Code
Ruger, Jennifer Prah; Lazar, Christina M (2012) Economic evaluation of drug abuse treatment and HIV prevention programs in pregnant women: a systematic review. Addict Behav 37:1-10
Ruger, Jennifer Prah (2012) Global health governance as shared health governance. J Epidemiol Community Health 66:653-61
Ruger, Jennifer Prah (2012) Author Response to Letter to the Editor: Making Power Visible in Global Health Governance. Am J Bioeth 12:65
Ruger, Jennifer Prah; Chawarski, Marek; Mazlan, Mahmud et al. (2012) Costs of addressing heroin addiction in Malaysia and 32 comparable countries worldwide. Health Serv Res 47:865-87
Ruger, Jennifer Prah; Lazar, Christina M (2012) Economic evaluation of pharmaco- and behavioral therapies for smoking cessation: a critical and systematic review of empirical research. Annu Rev Public Health 33:279-305
Ruger, Jennifer Prah (2011) Shared health governance. Am J Bioeth 11:32-45
Ng, Nora Y; Ruger, Jennifer Prah (2011) Global Health Governance at a Crossroads. Glob Health Gov 3:1-37
Ruger, Jennifer Prah (2011) Reply. J Human Dev Capabil 12:599-605
Ruger, Jennifer Prah (2010) Health capability: conceptualization and operationalization. Am J Public Health 100:41-9
Kim, Hak-Ju; Ruger, Jennifer Prah (2010) Socioeconomic disparities in behavioral risk factors and health outcomes by gender in the Republic of Korea. BMC Public Health 10:195

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