Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01DK062903-02
Application #
6706196
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
2003-02-15
Project End
2005-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$86,701
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Finck, Brian N (2007) The PPAR regulatory system in cardiac physiology and disease. Cardiovasc Res 73:269-77
Finck, Brian N; Kelly, Daniel P (2006) PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J Clin Invest 116:615-22
Wolins, Nathan E; Quaynor, Benjamin K; Skinner, James R et al. (2006) OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization. Diabetes 55:3418-28
Finck, Brian N; Gropler, Matthew C; Chen, Zhouji et al. (2006) Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway. Cell Metab 4:199-210
Burgess, Shawn C; Leone, Teresa C; Wende, Adam R et al. (2006) Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice. J Biol Chem 281:19000-8
Russell, Laurie K; Finck, Brian N; Kelly, Daniel P (2005) Mouse models of mitochondrial dysfunction and heart failure. J Mol Cell Cardiol 38:81-91
Finck, Brian N; Bernal-Mizrachi, Carlos; Han, Dong Ho et al. (2005) A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes. Cell Metab 1:133-44
Finck, Brian N (2004) The role of the peroxisome proliferator-activated receptor alpha pathway in pathological remodeling of the diabetic heart. Curr Opin Clin Nutr Metab Care 7:391-6