The goal of this Research Career Award is to elaborate on the mechanisms that link genetic characteristics and the social environment to 2 important outcomes among adolescents and young adults: (1) ill-health and (2) delinquency. This project will pay particular attention to the social context in which known genetic risk factors are given expression as well as genetic characteristics that facilitate resiliency in the face of social disadvantage. The project will build on the existing infrastructural capacity, cross-disciplinary collaboration, and mentorship available at the University of Colorado at Boulder in the emerging discipline of behavioral genetics. This training proposal includes: (1) direct instruction and supervision by leading experts in the substantive and methodological area of behavioral genetics, (2) enrollment in courses and seminars by researchers in social science, behavioral science, and medical science disciplines, (3) participation in workshops in sibling association and linkage analysis methodologies, and (4) regular participation in national conferences in population studies and behavioral genetics. The research proposal aims to utilize data from the National Longitudinal Study of Adolescent Health and the Rochester Youth Developmental Survey in conjunction with genetic information of respondents to examine the interaction between biological characteristics of individuals and their immediate social environment as determinants of differential developmental trajectories in the early stages of the life course. The long-term goal of this project is to collect original data in an effort to highlight the social determinants of genetic expression. These studies would be structured around the hypotheses and findings that stem from this project.
| Boardman, Jason D; Barnes, Lisa L; Wilson, Robert S et al. (2012) Social disorder, APOE-E4 genotype, and change in cognitive function among older adults living in Chicago. Soc Sci Med 74:1584-90 |
| Boardman, Jason D; Alexander, Kari B; Stallings, Michael C (2011) Stressful life events and depression among adolescent twin pairs. Biodemography Soc Biol 57:53-66 |
| Boardman, Jason D; Blalock, Casey L; Pampel, Fred C et al. (2011) Population composition, public policy, and the genetics of smoking. Demography 48:1517-33 |
| Boardman, Jason D; Alexander, Kari B (2011) Stress trajectories, health behaviors, and the mental health of black and white young adults. Soc Sci Med 72:1659-66 |
| Sakai, Joseph T; Boardman, Jason D; Gelhorn, Heather L et al. (2010) Using trajectory analyses to refine phenotype for genetic association: conduct problems and the serotonin transporter (5HTTLPR). Psychiatr Genet 20:199-206 |
| Boardman, Jason D; Blalock, Casey L; Pampel, Fred C (2010) Trends in the genetic influences on smoking. J Health Soc Behav 51:108-23 |
| Boardman, Jason D; Blalock, Casey L; Corley, Robin P et al. (2010) Ethnicity, body mass, and genome-wide data. Biodemography Soc Biol 56:123-36 |
| Haberstick, Brett C; Lessem, Jeffery M; McQueen, Matthew B et al. (2010) Stable genes and changing environments: body mass index across adolescence and young adulthood. Behav Genet 40:495-504 |
| Boardman, Jason D (2009) State-level moderation of genetic tendencies to smoke. Am J Public Health 99:480-6 |
| Button, Tanya M M; Stallings, Michael C; Rhee, Soo Hyun et al. (2009) Perceived peer delinquency and the genetic predisposition for substance dependence vulnerability. Drug Alcohol Depend 100:1-8 |
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