Major depressive disorder is the leading cause for disability among adolescents globally, and most young people do not receive treatment. Schools provide an unparalleled opportunity to reach early adolescents and reduce the global mental health treatment gap. Situated throughout urban and rural areas, schools are often located in communities with few-to-no other social service or health infrastructure. Growing evidence indicates that mental health treatment can be effectively delivered in low-resource schools by non-mental health professionals. However, a lack of research exists on schools-based treatment interventions for depression, especially in low and middle-income countries, or how to implement them within educational systems. This K01 proposes a multi-phase research study to implement Group Interpersonal Psychotherapy for Depressed Adolescents (IPT-G-A) in schools in Uganda. IPT-G-A is a manualized depression intervention that has demonstrated effectiveness with adolescents in Uganda, but has not yet been implemented or scaled-up in school settings. This project aims to understand the factors relevant to implementation and effectiveness of depression treatment in Ugandan schools and pilot a strategy for implementing IPT-G-A, leveraging an existing violence prevention program called the Good School Toolkit (GST). This study has three specific aims.
The first aim i s to examine factors relevant to the implementation and effectiveness of school-based interventions through secondary analysis of data from the GST effectiveness trial. Next, the project aims to determining the contextual and cultural influences on the implementation of IPT-G-A in schools leveraging the GST through qualitative methods.
The third aim i s to examine the acceptability and feasibility of implementing IPT-G-A for early adolescents with elevated internalizing symptoms through a pilot in 2 Ugandan primary schools currently using the GST. These research activities will be combined with a comprehensive training program that integrates didactic lectures and mentored experiences. Led by Primary Mentor, Dr. Myrna Weissman, the plan includes the following goals: (1) to expand knowledge about parameters that are relevant to effectiveness and implementation of mental health interventions for adolescents; (2); to develop expertise in how to improve adoption of evidence-based interventions in school-based settings using community engagement approaches and (3) to learn and apply principles of hybrid effectiveness- implementation designs. This training will support my long-term career goal to become an independent investigator in effectiveness and implementation science for global mental health with a focus on adolescence. The research plan will produce data for a R01 to conduct a Type 2 Hybrid Effectiveness- Implementation Study on IPT-G-A in Ugandan schools leveraging the GST.

Public Health Relevance

Implementing depression treatment in schools has the potential to reduce the global mental health treatment gap for adolescents in low-resource settings. This K01 Career Development Award will prepare the candidate to implement depression treatment for early adolescents in Ugandan schools by gaining expertise in the parameters relevant to the effectiveness and implementation of adolescent mental health interventions, adoption of EBIs in school-based settings, and hybrid effectiveness and implementation research designs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01MH110651-04
Application #
9990858
Study Section
Mental Health Services Research Committee (SERV)
Program Officer
Allison, Susannah
Project Start
2017-08-08
Project End
2021-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
4
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Alabama in Tuscaloosa
Department
Type
University-Wide
DUNS #
045632635
City
Tuscaloosa
State
AL
Country
United States
Zip Code
35487
Namy, Sophie; Carlson, Catherine; O'Hara, Kathleen et al. (2017) Towards a feminist understanding of intersecting violence against women and children in the family. Soc Sci Med 184:40-48
Namy, Sophie; Carlson, Catherine; Norcini Pala, Andrea et al. (2017) Gender, violence and resilience among Ugandan adolescents. Child Abuse Negl 70:303-314