This is a proposal for an NIH K02 Independent Scientist Award (ISA) for Deborah Hasin, Ph.D. The purpose of the award would be to enhance the development of Dr. Hasin's scientific abilities, to expand her overall potential to contribute to alcohol research and the understanding of alcohol use disorders, and to provide her with ongoing support to conduct independent, original research. During the next five years, Dr. Hasin proposes to continue the program of research she has been building at Columbia University (College of Physicians and Surgeons, Department of Psychiatry and School of Public Health, Division of Epidemiology). This program is focused on three areas begun during the previous K02 award, including (1) investigation of the validity of concepts and definitions of alcohol use disorders; (2) instrument development: measures for the reliable and valid diagnosis of psychiatric disorders in heavy drinkers or drug users; and (3) investigation of the effects of psychiatric comorbidity on the course of alcohol and drug use disorders. Dr. Hasin proposes to expand her knowledge base and skills to conduct research in two new areas, (1) instrument development of reliable and valid measures of HIV sex risk behaviors in alcohol- and drug-abusing samples, and (2) investigation of the effects of acculturation on drinking and the prevalence of alcohol disorders among Russian immigrants to the United States and Israel. Dr. Hasin is PI on a grant that funds the study of comorbidity and course of alcohol and drug disorders. She has a proposal pending to test DSM-IV developments in a psychiatric diagnostic interview for comorbidity that she developed. Dr. Hasin's program of research will be carried out through analysis of data she has already collected, through completion of data collection and analyses now underway, and through initiation of new data collection projects. Dr. Hasin's scientific development and research will be enhanced through course work and readings. She will also receive training and consultation from experts in clinical research, in HIV sexual risk behaviors, in drinking practices and problems in Israel, and in the culture of Russian immigrants to the U.S. and Israel. She will collaborate with these experts in later years of the award. If received, the ISA will enable Dr. Hasin to focus on her research, on developing new skills and knowledge, and contributing to an understanding of alcohol use disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Scientist Development Award - Research (K02)
Project #
2K02AA000161-06
Application #
2697446
Study Section
Special Emphasis Panel (ZAA1-FF (01))
Project Start
1993-07-01
Project End
2003-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
6
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Psychiatry
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Alegria, Analucia A; Blanco, Carlos; Petry, Nancy M et al. (2013) Sex differences in antisocial personality disorder: results from the National Epidemiological Survey on Alcohol and Related Conditions. Personal Disord 4:214-22
Sugaya, Luisa; Hasin, Deborah S; Olfson, Mark et al. (2012) Child physical abuse and adult mental health: a national study. J Trauma Stress 25:384-92
Lopes, Mariana; Olfson, Mark; Rabkin, Judith et al. (2012) Gender, HIV status, and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 73:384-91
Oquendo, Maria A; Currier, Dianne; Liu, Shang-Min et al. (2010) Increased risk for suicidal behavior in comorbid bipolar disorder and alcohol use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). J Clin Psychiatry 71:902-9
Schneier, F R; Foose, T E; Hasin, D S et al. (2010) Social anxiety disorder and alcohol use disorder co-morbidity in the National Epidemiologic Survey on Alcohol and Related Conditions. Psychol Med 40:977-88
Hasin, Deborah S; Grant, Bridget F (2002) Major depression in 6050 former drinkers: association with past alcohol dependence. Arch Gen Psychiatry 59:794-800
Hasin, Deborah; Aharonovich, Efrat; Liu, Xinhua et al. (2002) Alcohol dependence symptoms and alcohol dehydrogenase 2 polymorphism: Israeli Ashkenazis, Sephardics, and recent Russian immigrants. Alcohol Clin Exp Res 26:1315-21
Aharonovich, E; Hasin, D; Rahav, G et al. (2001) Differences in drinking patterns among Ashkenazic and Sephardic Israeli adults. J Stud Alcohol 62:301-5
Hasin, D; Paykin, A; Endicott, J (2001) Course of DSM-IV alcohol dependence in a community sample: effects of parental history and binge drinking. Alcohol Clin Exp Res 25:411-4
Hasin, D; Liu, X; Paykin, A (2001) DSM-IV alcohol dependence and sustained reduction in drinking: investigation in a community sample. J Stud Alcohol 62:509-17

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