Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02DA000130-05
Application #
2115956
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1992-09-01
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Xu, W; Huang, L F; Bauer, L et al. (1999) Synthesis and opiate receptor binding properties of 17-methyl-6,7-dehydro-3,14-dihydroxy-4,5alpha-epoxy-6,7:4',5'-pyrimidin omorphinans. Bioorg Med Chem Lett 9:3375-80
Bhargava, H N; Kumar, S (1999) Sensitization to the locomotor stimulant effect of cocaine modifies the binding of [3H]MK-801 to brain regions and spinal cord of the mouse. Gen Pharmacol 32:359-63
Bian, J T; Bhargava, H N (1998) Effect of chronic administration of L-arginine, NG-nitro-L-arginine or their combination on morphine concentration in peripheral tissues and urine of the mouse. Gen Pharmacol 30:753-7
Bhargava, H N; Kumar, S; Barjavel, M J (1998) Kinetic properties of nitric oxide synthase in cerebral cortex and cerebellum of morphine tolerant mice. Pharmacology 56:252-6
Bhargava, H N; Bian, J T (1998) Effects of acute administration of L-arginine on morphine antinociception and morphine distribution in central and peripheral tissues of mice. Pharmacol Biochem Behav 61:29-33
Sunder Sharma, S; Bhargava, H N (1998) Enhancement of morphine antinociception by ibogaine and noribogaine in morphine-tolerant mice. Pharmacology 57:229-32
Bhargava, H N; Villar, V M; Cortijo, J et al. (1998) Analgesic and thermic effects, and cerebrospinal fluid and plasma pharmacokinetics, of intracerebroventricularly administered morphine in normal and sensitized rats. J Pharm Pharmacol 50:197-203
Bhargava, H N; Cao, Y J (1998) Interactions of cocaine with morphine, U-50,488H and [D-Pen2, D-Pen5]enkaphalin. Peptides 19:563-8
Bhargava, H N; Sharma, S S; Bian, J T (1998) Evidence for a role of N-methyl-D-aspartate receptors in L-arginine-induced attenuation of morphine antinociception. Brain Res 782:314-7
Bhargava, H N; Cao, Y J (1998) Effect of chronic administration of [D-Pen2, D-Pen5] enkephalin on the activity of nitric oxide synthase in brain regions and spinal cord of mice. Peptides 19:113-7

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