Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02DA000179-05
Application #
2116061
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Program Officer
Hillery, Paul
Project Start
1992-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1998-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Vaughan, Roxanne A; Parnas, M Laura; Gaffaney, Jon D et al. (2005) Affinity labeling the dopamine transporter ligand binding site. J Neurosci Methods 143:33-40
Reed, Brian; Chen, Nianhang; Justice Jr, Joseph B (2003) Dual-electrode voltammetry of catecholamine transport: simultaneous monitoring of uptake and efflux. J Neurosci Methods 126:127-35
Schad, Christina A; Justice Jr, Joseph B; Holtzman, Stephen G (2002) Endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions. J Pharmacol Exp Ther 300:932-8
Chen, N; Justice, J B (2000) Differential effect of structural modification of human dopamine transporter on the inward and outward transport of dopamine. Brain Res Mol Brain Res 75:208-15
Gong, W; Neill, D B; Lynn, M et al. (1999) Dopamine D1/D2 agonists injected into nucleus accumbens and ventral pallidum differentially affect locomotor activity depending on site. Neuroscience 93:1349-58
Chen, N; Trowbridge, C G; Justice Jr, J B (1999) Cationic modulation of human dopamine transporter: dopamine uptake and inhibition of uptake. J Pharmacol Exp Ther 290:940-9
Danek Burgess, K S; Justice Jr, J B (1999) Effects of serine mutations in transmembrane domain 7 of the human norepinephrine transporter on substrate binding and transport. J Neurochem 73:656-64
Danek, K; Justice Jr, J B (1998) Voltammetric studies on kinetics of uptake and efflux at catecholamine transporters. Methods Enzymol 296:649-60
Chen, N; Trowbridge, C G; Justice Jr, J B (1998) Voltammetric studies on mechanisms of dopamine efflux in the presence of substrates and cocaine from cells expressing human norepinephrine transporter. J Neurochem 71:653-65
Chen, N; Justice Jr, J B (1998) Cocaine acts as an apparent competitive inhibitor at the outward-facing conformation of the human norepinephrine transporter: kinetic analysis of inward and outward transport. J Neurosci 18:10257-68

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