This is an application for a K02 Independent Scientist Award in response to PA-95-050. The award will permit the applicant to obtain additional training and education and to develop a funded R01 program in health services research for drug use disorders. The investigator's proposed research plan studies the relationship between health care utilization and patient outcomes in individuals with drug use disorders and comorbid medical (including HIV/AIDS) and psychiatric conditions. The research will be conducted largely within a rural context to provide critical information about this largely understudied population of drug users. The investigator is an experienced and funded health services researcher in alcohol use disorders. She proposes a natural progression from a single substance use disorder, alcohol, to the larger issues of services and outcomes for the range of drug use disorders. She has identified a number of methodological and substantive issues for which to obtain training during this five-year award and outlines specific educational programs and mentoring groups to assist in this effort.
The specific aims of her proposed research plan are: 1. To develop a stronger scientific understanding of the unique aspects of drug use disorders, the unique scientific issues, and the broad array of health services proved to these individuals; 2. To understand how treatment services or other health services are provided to rural individuals with drug use disorders and to individuals with comorbidity including HIV/AIDS and the outcomes of these services; and 3. To develop a research knowledge of individuals with drug use disorders in medical settings, including emergency departments and primary care, particularly for rural residents and individuals with comorbid medical (including HIV/AIDS) or psychiatric conditions. To accomplish this research plan, the investigator proposes to conduct three projects: (1 ) Availability of Drug Treatment Services and Outcomes for Individuals with Drug Use Disorders and Comorbidity; (2) Detection, Management, and Health Care Outcomes for Individuals with Drug Use Disorders in Emergency Department Settings; and (3) Development of Conceptual and Theoretic Work about Comorbidity in Drug Use Disorders.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Scientist Development Award - Research (K02)
Project #
Application #
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Hilton, Thomas
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Arkansas for Medical Sciences
Schools of Medicine
Little Rock
United States
Zip Code
Booth, Brenda M; Curran, Geoffrey M; Han, Xiaotong (2004) Predictors of short-term course of drinking in untreated rural and urban at-risk drinkers: effects of gender, illegal drug use and psychiatric comorbidity. J Stud Alcohol 65:63-73
Fortney, John; Mukherjee, Snigdha; Curran, Geoffrey et al. (2004) Factors associated with perceived stigma for alcohol use and treatment among at-risk drinkers. J Behav Health Serv Res 31:418-29
Fortney, John C; Booth, Brenda M; Kirchner, JoAnn E et al. (2003) Differences between physical and behavioral health benefits in the health plans of at-risk drinkers. Psychiatr Serv 54:97-102
Kramer, Teresa L; Booth, Brenda M; Han, Xiaotong et al. (2003) Service utilization and outcomes in medically ill veterans with posttraumatic stress and depressive disorders. J Trauma Stress 16:211-9
Fortney, John C; Booth, Brenda M; Kirchner, JoAnn E et al. (2003) Rural-urban differences in health care benefits of a community-based sample of at-risk drinkers. J Rural Health 19:292-8
Kirchner, JoAnn E; Curran, Geoffrey M; Thrush, Carol R et al. (2002) Depressive disorders and alcohol dependence in a community population. Community Ment Health J 38:361-73
Curran, Geoffrey M; Kirchner, JoAnn E; Worley, Mark et al. (2002) Depressive symptomatology and early attrition from intensive outpatient substance use treatment. J Behav Health Serv Res 29:138-43
Booth, Brenda M; Feng, Weiwei (2002) The impact of drinking and drinking consequences on short-term employment outcomes in at-risk drinkers in six southern states. J Behav Health Serv Res 29:157-66
Booth, Brenda M; Sullivan, Greer; Koegel, Paul et al. (2002) Vulnerability factors for homelessness associated with substance dependence in a community sample of homeless adults. Am J Drug Alcohol Abuse 28:429-52
Booth, B M; Fortney, S M; Fortney, J C et al. (2001) Short-term course of drinking in an untreated sample of at-risk drinkers. J Stud Alcohol 62:580-8

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