Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02ES000299-05
Application #
6178707
Study Section
Chemical Pathology Study Section (CPA)
Program Officer
Velazquez, Jose M
Project Start
1996-05-01
Project End
2000-08-31
Budget Start
2000-05-01
Budget End
2000-08-31
Support Year
5
Fiscal Year
2000
Total Cost
$11,838
Indirect Cost

  Institution

Name
Harvard University
Department
Genetics
Type
Schools of Public Health
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Reliene, Ramune; Fischer, Elvira; Schiestl, Robert H (2004) Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res 64:5148-53
Rugo, Rebecca E; Schiestl, Robert H (2004) Increases in oxidative stress in the progeny of X-irradiated cells. Radiat Res 162:416-25
Reliene, Ramune; Bishop, Alexander J R; Li, Gloria et al. (2004) Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice. DNA Repair (Amst) 3:103-11
Secretan, M B; Scuric, Z; Oshima, J et al. (2004) Effect of Ku86 and DNA-PKcs deficiency on non-homologous end-joining and homologous recombination using a transient transfection assay. Mutat Res 554:351-64
Reliene, Ramune; Bishop, Alexander J R; Aubrecht, Jiri et al. (2004) In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol Biol 262:125-39
Egorov, Andrey I; Howlett, Niall G; Schiestl, Robert H (2004) Mutagen X and chlorinated tap water are recombinagenic in yeast. Mutat Res 563:159-69
Reliene, Ramune; Schiestl, Robert H (2003) Mouse models for induced genetic instability at endogenous loci. Oncogene 22:7000-10
Bishop, Alexander J R; Hollander, M Christine; Kosaras, Bela et al. (2003) Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res 63:5335-43
Rugo, R E; Secretan, M B; Schiestl, R H (2002) X radiation causes a persistent induction of reactive oxygen species and a delayed reinduction of TP53 in normal human diploid fibroblasts. Radiat Res 158:210-9
Davidson, J F; Schiestl, R H (2001) Mitochondrial respiratory electron carriers are involved in oxidative stress during heat stress in Saccharomyces cerevisiae. Mol Cell Biol 21:8483-9

Showing the most recent 10 out of 17 publications