This is a proposal for an Independent Scientist Award (KO2) to expand the applicant's research program on behavioral interventions for obesity in youth, to prevent cardiovascular risk factors and disease Limited progress in obesity treatment and maintenance of weight loss argues for a focus on improving current treatments and for translating basic behavioral science to clinical research.
The aim of this application is t develop a multilevel approach for studying behavioral treatments for obesity in youth by pursuing specialized collaborations and advanced training. The three career goals outlined in this application are 1) To gain further knowledge and experiences to substantially contribute to the field of the treatment of obesity in youth, 2) To work toward optimizing currently available approaches for child obesity treatment, and to create translatable versions of these treatments for the clinic and 3) To identify highly novel targets for the treatment of children who are overweight and obese, based on findings from basic behavioral sciences and on neuroscience. Career development activities include consultations with colleagues working in basic behavioral sciences and neuroscience, and formal course work, hands-on training, and collaboration with experts in neuroimaging. Support of this application will allow the PI the much needed time to focus on research and develop a base of basic behavioral sciences knowledge and neurobiological understanding of obesity and overeating. This application will allow Dr. Boutelle to gain the knowledge to conduct productive translational research to improve and develop obesity interventions, and maximize her contributions to the field.

Public Health Relevance

The purpose of this application is to support protected research time for Dr. Boutelle to gain further knowledge and experiences that will allow her to significantly contribute to the field of child obesity treatment.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Scientist Development Award - Research (K02)
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Special Emphasis Panel (ZHL1-CSR-K (O1))
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Czajkowski, Susan
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University of California San Diego
Schools of Medicine
La Jolla
United States
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Eichen, Dawn M; Matheson, Brittany E; Liang, June et al. (2018) The relationship between executive functioning and weight loss and maintenance in children and parents participating in family-based treatment for childhood obesity. Behav Res Ther 105:10-16
Eichen, Dawn M; Matheson, Brittany E; Appleton-Knapp, Sara L et al. (2017) Neurocognitive Treatments for Eating Disorders and Obesity. Curr Psychiatry Rep 19:62
Mestre, Z L; Bischoff-Grethe, A; Eichen, D M et al. (2017) Hippocampal atrophy and altered brain responses to pleasant tastes among obese compared with healthy weight children. Int J Obes (Lond) 41:1496-1502
Boutelle, Kerri N; Monreal, Teresa; Strong, David R et al. (2016) An open trial evaluating an attention bias modification program for overweight adults who binge eat. J Behav Ther Exp Psychiatry 52:138-146
Liang, June; Matheson, Brittany E; Rhee, Kyung E et al. (2016) Parental control and overconsumption of snack foods in overweight and obese children. Appetite 100:181-8
Boutelle, Kerri N; Braden, Abby; Douglas, Jennifer M et al. (2015) Design of the FRESH study: A randomized controlled trial of a parent-only and parent-child family-based treatment for childhood obesity. Contemp Clin Trials 45:364-370
Braden, Abby; Strong, David; Crow, Scott et al. (2015) Parent changes in diet, physical activity, and behavior in family-based treatment for childhood obesity. Clin Pediatr (Phila) 54:494-7
Boutelle, K N; Wierenga, C E; Bischoff-Grethe, A et al. (2015) Increased brain response to appetitive tastes in the insula and amygdala in obese compared with healthy weight children when sated. Int J Obes (Lond) 39:620-8
Boutelle, Kerri N; Liang, June; Knatz, Stephanie et al. (2015) Design and implementation of a study evaluating extinction processes to food cues in obese children: the Intervention for Regulations of Cues Trial (iROC). Contemp Clin Trials 40:95-104
Boutelle, Kerri N; Bouton, Mark E (2015) Implications of learning theory for developing programs to decrease overeating. Appetite 93:62-74

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