This proposal for an independent Scientist Award (K02) to support my research program in the area of the treatment and outcome of eating disorders. This has been the focus of my work since finishing residency in 1992 and since 1995 I have been the principal investigator of an active and productive research group focused on eating disorders treatment and outcome issues. The application centers around R01 grant """"""""Stepped Care vs. Best Available care for Bulimia Nervosa"""""""" (R01-MH-59304). This is a five year study (now in its third year) examining the use of different sequences of self-help, pharmacotherapy, and cognitive behavioral therapy to treat bulimia nervosa. In addition to measuring the efficacy of these various treatment packages, cost efficacy will also be measured. The Department of Psychiatry at the University of Minnesota has made a strong institutional commitment to this award. The department provides strong administrative support and a highly supportive environment for research activities, and recently completed construction of a 4000 square feet Psychiatry Ambulatory Research Center (ARC) that houses my ongoing research activities. If funded, this award will free me up from substantial clinical duties and protect fully 75% of my time for research activities. This increased time will allow for advanced specialized training in cost efficacy analysis, specific training in sophisticated clinical outcomes research techniques through the Clinical Outcomes Research Center at the University of Minnesota, active consultation regarding ED treatment study issues with B. Timothy Walsh, M.D and active consultation on eating disorder course and outcome study issues with Christopher Fairbum, M.D. These career development activities will enable me to utilize the unique research populations and data available at Minnesota to pursue my research goals in the areas of studying effective and cost effective treatment for eating disorders and examining their course and their costs. Numerous studies are planned during this award and in the years that follow to leverage these new skills and unique resources.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02MH065919-03
Application #
6863667
Study Section
Interventions Research Review Committee (ITV)
Program Officer
Street, Linda L
Project Start
2003-04-01
Project End
2008-02-29
Budget Start
2005-03-01
Budget End
2006-02-28
Support Year
3
Fiscal Year
2005
Total Cost
$137,793
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Psychiatry
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Pacanowski, Carly R; Mason, Tyler B; Crosby, Ross D et al. (2018) Weight Change over the Course of Binge Eating Disorder Treatment: Relationship to Binge Episodes and Psychological Factors. Obesity (Silver Spring) 26:838-844
Levis, Brooke; Benedetti, Andrea; Riehm, Kira E et al. (2018) Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews. Br J Psychiatry 212:377-385
Peterson, Carol B; Berg, Kelly C; Crosby, Ross D et al. (2017) The effects of psychotherapy treatment on outcome in bulimia nervosa: Examining indirect effects through emotion regulation, self-directed behavior, and self-discrepancy within the mediation model. Int J Eat Disord 50:636-647
Levis, Brooke; Benedetti, Andrea; Levis, Alexander W et al. (2017) Selective Cutoff Reporting in Studies of Diagnostic Test Accuracy: A Comparison of Conventional and Individual-Patient-Data Meta-Analyses of the Patient Health Questionnaire-9 Depression Screening Tool. Am J Epidemiol 185:954-964
Lavender, Jason M; Mason, Tyler B; Utzinger, Linsey M et al. (2016) Examining affect and perfectionism in relation to eating disorder symptoms among women with anorexia nervosa. Psychiatry Res 241:267-72
Goldschmidt, Andrea B; Accurso, Erin C; Crosby, Ross D et al. (2016) Association between objective and subjective binge eating and psychopathology during a psychological treatment trial for bulimic symptoms. Appetite 107:471-477
Mason, Tyler B; Lavender, Jason M; Wonderlich, Stephen A et al. (2016) The role of interpersonal personality traits and reassurance seeking in eating disorder symptoms and depressive symptoms among women with bulimia nervosa. Compr Psychiatry 68:165-71
Peterson, Carol B; Pisetsky, Emily M; Swanson, Sonja A et al. (2016) Examining the utility of narrowing anorexia nervosa subtypes for adults. Compr Psychiatry 67:54-8
Smith, Christina E; Pisetsky, Emily M; Wonderlich, Stephen A et al. (2016) Is childhood trauma associated with lifetime suicide attempts in women with bulimia nervosa? Eat Weight Disord 21:199-204
Pisetsky, Emily M; Wonderlich, Stephen A; Crosby, Ross D et al. (2015) Depression and Personality Traits Associated With Emotion Dysregulation: Correlates of Suicide Attempts in Women with Bulimia Nervosa. Eur Eat Disord Rev 23:537-44

Showing the most recent 10 out of 47 publications