Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Modified Research Career Development Award (K04)
Project #
5K04AI001162-04
Application #
2057262
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1993-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Seyfang, A; Landfear, S M (2000) Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter. J Biol Chem 275:5687-93
Seyfang, A; Landfear, S M (1999) Substrate depletion upregulates uptake of myo-inositol, glucose and adenosine in Leishmania. Mol Biochem Parasitol 104:121-30
Snapp, E L; Landfear, S M (1999) Characterization of a targeting motif for a flagellar membrane protein in Leishmania enriettii. J Biol Chem 274:29543-8
Vasudevan, G; Carter, N S; Drew, M E et al. (1998) Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant. Proc Natl Acad Sci U S A 95:9873-8
Burchmore, R J; Landfear, S M (1998) Differential regulation of multiple glucose transporter genes in Leishmania mexicana. J Biol Chem 273:29118-26
Seyfang, A; Kavanaugh, M P; Landfear, S M (1997) Aspartate 19 and glutamate 121 are critical for transport function of the myo-inositol/H+ symporter from Leishmania donovani. J Biol Chem 272:24210-5
Snapp, E L; Landfear, S M (1997) Cytoskeletal association is important for differential targeting of glucose transporter isoforms in Leishmania. J Cell Biol 139:1775-83
Klamo, E M; Drew, M E; Landfear, S M et al. (1996) Kinetics and stoichiometry of a proton/myo-inositol cotransporter. J Biol Chem 271:14937-43
Drew, M E; Langford, C K; Klamo, E M et al. (1995) Functional expression of a myo-inositol/H+ symporter from Leishmania donovani. Mol Cell Biol 15:5508-15
Langford, C K; Kavanaugh, M P; Stenberg, P E et al. (1995) Functional expression and subcellular localization of a high-Km hexose transporter from Leishmania donovani. Biochemistry 34:11814-21

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