Molecular Mechanisms of Cell Interactions with Collagens

Fields, Gregg B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Modified Research Career Development Award (K04)
• Project #: 5K04AR001929-03
• Application #: 2077499
• Study Section: Biochemistry Study Section (BIO)
• Project Start: 1994-03-01
• Project End: 1999-02-28
• Budget Start: 1996-03-01
• Budget End: 1997-02-28
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Minnesota Twin Cities
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 168559177
• City: Minneapolis
• State: MN
• Country: United States
• Zip Code: 55455

Publications

Lauer-Fields, Janelle L; Fields, Gregg B (2002) Triple-helical peptide analysis of collagenolytic protease activity. Biol Chem 383:1095-105

Malkar, Navdeep B; Lauer-Fields, Janelle L; Borgia, Jeffrey A et al. (2002) Modulation of triple-helical stability and subsequent melanoma cellular responses by single-site substitution of fluoroproline derivatives. Biochemistry 41:6054-64

Lauer-Fields, Janelle L; Juska, Darius; Fields, Gregg B (2002) Matrix metalloproteinases and collagen catabolism. Biopolymers 66:19-32

Lauer-Fields, J L; Broder, T; Sritharan, T et al. (2001) Kinetic analysis of matrix metalloproteinase activity using fluorogenic triple-helical substrates. Biochemistry 40:5795-803

Edwards, W B; Anderson, C J; Fields, G B et al. (2001) Evaluation of radiolabeled type IV collagen fragments as potential tumor imaging agents. Bioconjug Chem 12:1057-65

Fields, G B (2001) Using fluorogenic peptide substrates to assay matrix metalloproteinases. Methods Mol Biol 151:495-518

Forns, P; Lauer-Fields, J L; Gao, S et al. (2000) Induction of protein-like molecular architecture by monoalkyl hydrocarbon chains. Biopolymers 54:531-46

Lauer-Fields, J L; Nagase, H; Fields, G B (2000) Use of Edman degradation sequence analysis and matrix-assisted laser desorption/ionization mass spectrometry in designing substrates for matrix metalloproteinases. J Chromatogr A 890:117-25

Borgia, J A; Fields, G B (2000) Chemical synthesis of proteins. Trends Biotechnol 18:243-51

Lauer-Fields, J L; Tuzinski, K A; Shimokawa, K i et al. (2000) Hydrolysis of triple-helical collagen peptide models by matrix metalloproteinases. J Biol Chem 275:13282-90