Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Modified Research Career Development Award (K04)
Project #
1K04CA001112-01
Application #
3071663
Study Section
Experimental Immunology Study Section (EI)
Project Start
1987-09-10
Project End
1992-08-31
Budget Start
1987-09-10
Budget End
1988-08-31
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Coppola, M A; Lam, T M; Strawbridge, R R et al. (1995) Recognition of endogenous ecotropic murine leukaemia viruses by anti-AKR/Gross virus cytotoxic T lymphocytes (CTL): epitope variation in a CTL-resistant virus. J Gen Virol 76 ( Pt 3):635-41
Rich, R F; Green, W R (1995) Nonresponsiveness of AKR.H-2b congenic mice for anti-AKR/Gross MuLV CTL responses: involvement of inhibitory cells as defined by adoptive transfer experiments. Cell Immunol 160:139-51
Coppola, M A; Green, W R (1994) Cytotoxic T lymphocyte responses to the envelope proteins of endogenous ecotropic and mink cytopathic focus-forming murine leukemia viruses in H-2b mice. Virology 202:500-5
Green, W R; Crassi, K M; Schwarz, D A et al. (1994) Cytotoxic T lymphocytes directed against MAIDS-associated tumors and cells from mice infected by the LP-BM5 MAIDS defective retrovirus. Virology 200:292-6
Green, W R; Green, K A; Crassi, K M (1994) Adoptive transfer of polyclonal and cloned cytolytic T lymphocytes (CTL) specific for mouse AIDS-associated tumors is effective in preserving CTL responses: a measure of protection against LP-BM5 retrovirus-induced immunodeficiency. J Virol 68:4679-84
Schwarz, D A; Green, W R (1994) CTL responses to the gag polyprotein encoded by the murine AIDS defective retrovirus are strain dependent. J Immunol 153:436-41
Rich, R F; Mayes, B E; Abate, M I et al. (1993) Induction, via immunization with a monoclonal antiidiotypic antibody, of viral envelope specific Ab3 antisera that neutralize retrovirus infectivity. Viral Immunol 6:193-206
White, H D; Green, W R; Gine, N R (1993) Molecular cloning of infectious ecotropic murine leukemia virus AK7 from an emv-14-positive AKXL-5 mouse and the resistance of AK7 to recognition by cytotoxic T lymphocytes. J Virol 67:5045-50
Wegmann, K W; Rich, R F; Green, W R (1992) Generation of anti-AKR/gross murine leukemia virus cytotoxic T lymphocytes (CTL). An analysis of precursor CTL frequencies in the AKR.H-2b and C57BL/6 mouse strains. J Immunol 149:1593-8
Rich, R F; Fujii, T; Green, W R (1992) CD4-CD8+ T lymphocytes mediate AKR/gross murine leukemia virus nonresponsiveness in moderately aged AKR.H-2b:Fv-1b mice. J Immunol 148:2961-7

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