Evolution of Human Hepatitis B Virus Precore Variant

Shih, Chiaho

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Modified Research Career Development Award (K04)
• Project #: 5K04CA060163-05
• Application #: 2100823
• Study Section: Virology Study Section (VR)
• Project Start: 1992-09-01
• Project End: 1997-08-31
• Budget Start: 1996-09-01
• Budget End: 1997-08-31
• Support Year: 5
• Fiscal Year: 1996

Institution

• Name: University of Texas Medical Br Galveston
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 041367053
• City: Galveston
• State: TX
• Country: United States
• Zip Code: 77555

Publications

Tai, P C; Banik, D; Lin, G I et al. (1997) Novel and frequent mutations of hepatitis B virus coincide with a major histocompatibility complex class I-restricted T-cell epitope of the surface antigen. J Virol 71:4852-6

Hosono, S; Tai, P C; Wang, W et al. (1995) Core antigen mutations of human hepatitis B virus in hepatomas accumulate in MHC class II-restricted T cell epitopes. Virology 212:151-62

Yuan, T T; Faruqi, A; Shih, J W et al. (1995) The mechanism of natural occurrence of two closely linked HBV precore predominant mutations. Virology 211:144-56