Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Modified Research Career Development Award (K04)
Project #
5K04DK002090-04
Application #
2133782
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1993-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Lash, L H; Putt, D A; Brashear, W T et al. (1999) Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene. J Toxicol Environ Health A 56:1-21
Cummings, B S; Zangar, R C; Novak, R F et al. (1999) Cellular distribution of cytochromes P-450 in the rat kidney. Drug Metab Dispos 27:542-8
Lash, L H; Lipscomb, J C; Putt, D A et al. (1999) Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation. Drug Metab Dispos 27:351-9
Lash, L H; Putt, D A (1999) Renal cellular transport of exogenous glutathione: heterogeneity at physiological and pharmacological concentrations. Biochem Pharmacol 58:897-907
Lash, L H; Putt, D A; Zalups, R K (1998) Role of extracellular thiols in accumulation and distribution of inorganic mercury in rat renal proximal and distal tubular cells. J Pharmacol Exp Ther 285:1039-50
Lash, L H (1998) In vitro methods of assessing renal damage. Toxicol Pathol 26:33-42
Chen, Z; Lash, L H (1998) Evidence for mitochondrial uptake of glutathione by dicarboxylate and 2-oxoglutarate carriers. J Pharmacol Exp Ther 285:608-18
Lash, L H; Qian, W; Putt, D A et al. (1998) Glutathione conjugation of perchloroethylene in rats and mice in vitro: sex-, species-, and tissue-dependent differences. Toxicol Appl Pharmacol 150:49-57
Lash, L H; Visarius, T M; Sall, J M et al. (1998) Cellular and subcellular heterogeneity of glutathione metabolism and transport in rat kidney cells. Toxicology 130:1-15
Lash, L H; Qian, W; Putt, D A et al. (1998) Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences. Drug Metab Dispos 26:12-9

Showing the most recent 10 out of 21 publications