Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Modified Research Career Development Award (K04)
Project #
5K04HD000862-03
Application #
3073462
Study Section
Experimental Immunology Study Section (EI)
Project Start
1989-08-01
Project End
1994-03-31
Budget Start
1990-04-01
Budget End
1991-03-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Kielar, M L; Sicher, S C; Penfield, J G et al. (2000) Nitric oxide inhibits INFgamma-induced increases in CIITA mRNA abundance and activation of CIITA dependent genes--class II MHC, Ii and H-2M. Class II TransActivator. Inflammation 24:431-45
Lu, C Y; Penfield, J G; Khair-el-Din, T A et al. (1998) Docosahexaenoic acid, a constituent of fetal and neonatal serum, inhibits nitric oxide production by murine macrophages stimulated by IFN gamma plus LPS, or by IFN gamma plus Listeria monocytogenes. J Reprod Immunol 38:31-53
Khair-el-Din, T A; Sicher, S C; Vazquez, M A et al. (1996) Inhibition of macrophage nitric-oxide production and Ia-expression by docosahexaenoic acid, a constituent of fetal and neonatal serum. Am J Reprod Immunol 36:1-10
Khair-El-Din, T; Sicher, S C; Vazquez, M A et al. (1996) Transcription of the murine iNOS gene is inhibited by docosahexaenoic acid, a major constituent of fetal and neonatal sera as well as fish oils. J Exp Med 183:1241-6
Vazquez, M A; Sicher, S C; Wright, W J et al. (1995) Differential regulation of TNF-alpha production by listeriolysin-producing versus nonproducing strains of Listeria monocytogenes. J Leukoc Biol 58:556-62
Khair-el-Din, T A; Sicher, S C; Vazquez, M A et al. (1995) Docosahexaenoic acid, a major constituent of fetal serum and fish oil diets, inhibits IFN gamma-induced Ia-expression by murine macrophages in vitro. J Immunol 154:1296-306
Sicher, S C; Chung, G W; Vazquez, M A et al. (1995) Augmentation or inhibition of IFN-gamma-induced MHC class II expression by lipopolysaccharides. The roles of TNF-alpha and nitric oxide, and the importance of the sequence of signaling. J Immunol 155:5826-34
Sicher, S C; Vazquez, M A; Lu, C Y (1994) Inhibition of macrophage Ia expression by nitric oxide. J Immunol 153:1293-300
Lu, C Y; Khair-el-Din, T A; Dawidson, I A et al. (1994) Xenotransplantation. FASEB J 8:1122-30
Lu, C Y; Sicher, S C; Vazquez, M A (1993) Prevention and treatment of renal allograft rejection: new therapeutic approaches and new insights into established therapies. J Am Soc Nephrol 4:1239-56

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