Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Modified Research Career Development Award (K04)
Project #
7K04HL001615-06
Application #
3073929
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1987-07-01
Project End
1992-06-30
Budget Start
1991-08-01
Budget End
1992-06-30
Support Year
6
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Schmaier, A H (1997) Contact activation: a revision. Thromb Haemost 78:101-7
Heda, G D; Kehoe, K J; Mahdi, F et al. (1996) Phosphatase 2A participates in interferon-gamma's induced upregulation of C1 inhibitor mRNA expression. Blood 87:2831-8
Hasan, A A; Cines, D B; Ngaiza, J R et al. (1995) High-molecular-weight kininogen is exclusively membrane bound on endothelial cells to influence activation of vascular endothelium. Blood 85:3134-43
Gluszko, P; Undas, A; Amenta, S et al. (1994) Administration of gamma interferon in human subjects decreases plasminogen activation and fibrinolysis without influencing C1 inhibitor. J Lab Clin Med 123:232-40
Schmaier, A H; Dahl, L D; Rozemuller, A J et al. (1993) Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa. J Clin Invest 92:2540-5
Zini, J M; Schmaier, A H; Cines, D B (1993) Bradykinin regulates the expression of kininogen binding sites on endothelial cells. Blood 81:2936-46
Jiang, Y; Nawarawong, W; Meloni, F J et al. (1992) Insights on monoclonal antibodies to kininogens' heavy chain which influence kininogens' binding to platelets. Thromb Haemost 68:143-8
Jiang, Y P; Muller-Esterl, W; Schmaier, A H (1992) Domain 3 of kininogens contains a cell-binding site and a site that modifies thrombin activation of platelets. J Biol Chem 267:3712-7
Jiang, Y P; Schmaier, A H (1992) Characterization of cell binding and thrombin inhibitory regions on kininogens' heavy chain. Agents Actions Suppl 38 ( Pt 1):233-40
Meloni, F J; Gustafson, E J; Schmaier, A H (1992) High molecular weight kininogen binds to platelets by its heavy and light chains and when bound has altered susceptibility to kallikrein cleavage. Blood 79:1233-44

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