|
Skordos, K W; Skiles, G L; Laycock, J D et al. (1998) Evidence supporting the formation of 2,3-epoxy-3-methylindoline: a reactive intermediate of the pneumotoxin 3-methylindole. Chem Res Toxicol 11:741-9
|
|
Skiles, G L; Yost, G S (1996) Mechanistic studies on the cytochrome P450-catalyzed dehydrogenation of 3-methylindole. Chem Res Toxicol 9:291-7
|
|
Thornton-Manning, J; Appleton, M L; Gonzalez, F J et al. (1996) Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding. J Pharmacol Exp Ther 276:21-9
|
|
Smith, D J; Appleton, M L; Carlson, J R et al. (1996) Identification of beta-glucuronidase-resistant diastereomeric glucuronides of 3-hydroxy-3-methyloxindole formed during 3-methylindole metabolism in goats. Drug Metab Dispos 24:119-25
|
|
Ramakanth, S; Thornton-Manning, J R; Wang, H et al. (1994) Correlation between pulmonary cytochrome P450 transcripts and the organ-selective pneumotoxicity of 3-methylindole. Toxicol Lett 71:77-85
|
|
Smith, D J; Skiles, G L; Appleton, M L et al. (1993) Identification of goat and mouse urinary metabolites of the pneumotoxin, 3-methylindole. Xenobiotica 23:1025-44
|
|
Thornton-Manning, J R; Nichols, W K; Manning, B W et al. (1993) Metabolism and bioactivation of 3-methylindole by Clara cells, alveolar macrophages, and subcellular fractions from rabbit lungs. Toxicol Appl Pharmacol 122:182-90
|
|
Swaffar, D S; Harker, W G; Pomerantz, S C et al. (1992) Isolation, purification, and characterization of two new chemical decomposition products of methylazoxyprocarbazine. Drug Metab Dispos 20:632-42
|
|
Nichols, W K; Covington, M O; Seiders, C D et al. (1992) Bioactivation of halogenated hydrocarbons by rabbit pulmonary cells. Pharmacol Toxicol 71:335-9
|
|
Swaffar, D S; Pomerantz, S C; Harker, W G et al. (1992) Non-enzymatic activation of procarbazine to active cytotoxic species. Oncol Res 4:49-58
|
Showing the most recent 10 out of 25 publications
