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Sun, D; Funk, C D (1996) Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein. J Biol Chem 271:24055-62
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Funk, C D (1996) The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice. Biochim Biophys Acta 1304:65-84
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Chen, X S; Naumann, T A; Kurre, U et al. (1995) cDNA cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase. J Biol Chem 270:17993-9
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Funk, C D; Chen, X S; Kurre, U et al. (1995) Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene. Adv Prostaglandin Thromboxane Leukot Res 23:145-50
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Chen, X S; Kurre, U; Jenkins, N A et al. (1994) cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases. J Biol Chem 269:13979-87
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Kuchinke, W; Funk, C D (1994) Fibronectin-induced cell spreading and down-regulation of 12-lipoxygenase expression in megakaryocytic DAMI cells. Biochem Biophys Res Commun 204:606-12
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Funk, C D; Kurre, U; Griffis, G (1994) Targeted gene disruption by homologous recombination. Toward an understanding of specific blood cell functions. Ann N Y Acad Sci 714:253-8
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Romano, M; Chen, X S; Takahashi, Y et al. (1993) Lipoxin synthase activity of human platelet 12-lipoxygenase. Biochem J 296 ( Pt 1):127-33
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Funk, C D (1993) Molecular biology in the eicosanoid field. Prog Nucleic Acid Res Mol Biol 45:67-98
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Chen, X S; Funk, C D (1993) Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies. FASEB J 7:694-701
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