Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Modified Research Career Development Award (K04)
Project #
5K04HL003006-03
Application #
2210909
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1994-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Siragy, Helmy M (2010) The angiotensin II type 2 receptor and the kidney. J Renin Angiotensin Aldosterone Syst 11:33-6
Siragy, Helmy M; Xue, Chun (2008) Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats. Exp Physiol 93:817-24
Siragy, Helmy M; Huang, Jiqian (2008) Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity. Exp Physiol 93:709-14
Abdel-Rahman, Emaad M; Abadir, Peter M; Siragy, Helmy M (2008) Regulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT1 and AT2 receptors. Am J Physiol Regul Integr Comp Physiol 295:R1473-8
Siragy, Helmy M (2007) Angiotensin AT1 and AT2 receptors--the battle for health and disease. Nephrol Dial Transplant 22:3128-30
Siragy, Helmy M; Inagami, Tadashi; Carey, Robert M (2007) NO and cGMP mediate angiotensin AT2 receptor-induced renal renin inhibition in young rats. Am J Physiol Regul Integr Comp Physiol 293:R1461-7
Abadir, Peter M; Periasamy, Ammasi; Carey, Robert M et al. (2006) Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization. Hypertension 48:316-22
Xue, Chun; Siragy, Helmy M (2005) Local renal aldosterone system and its regulation by salt, diabetes, and angiotensin II type 1 receptor. Hypertension 46:584-90
Siragy, Helmy M; Xue, Chun; Abadir, Peter et al. (2005) Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. Hypertension 45:133-7
Awad, Alaa S; Webb, Randy L; Carey, Robert M et al. (2005) Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. Am J Hypertens 18:544-8

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