Paracrine Mechanisms of Renal Kinins

Siragy, Helmy M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Modified Research Career Development Award (K04)
• Project #: 5K04HL003006-03
• Application #: 2210909
• Study Section: Experimental Cardiovascular Sciences Study Section (ECS)
• Project Start: 1994-07-01
• Project End: 1999-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Virginia
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 001910777
• City: Charlottesville
• State: VA
• Country: United States
• Zip Code: 22904

Publications

Siragy, Helmy M (2010) The angiotensin II type 2 receptor and the kidney. J Renin Angiotensin Aldosterone Syst 11:33-6

Siragy, Helmy M; Xue, Chun (2008) Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats. Exp Physiol 93:817-24

Siragy, Helmy M; Huang, Jiqian (2008) Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity. Exp Physiol 93:709-14

Abdel-Rahman, Emaad M; Abadir, Peter M; Siragy, Helmy M (2008) Regulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT1 and AT2 receptors. Am J Physiol Regul Integr Comp Physiol 295:R1473-8

Siragy, Helmy M (2007) Angiotensin AT1 and AT2 receptors--the battle for health and disease. Nephrol Dial Transplant 22:3128-30

Siragy, Helmy M; Inagami, Tadashi; Carey, Robert M (2007) NO and cGMP mediate angiotensin AT2 receptor-induced renal renin inhibition in young rats. Am J Physiol Regul Integr Comp Physiol 293:R1461-7

Abadir, Peter M; Periasamy, Ammasi; Carey, Robert M et al. (2006) Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization. Hypertension 48:316-22

Siragy, Helmy M; Xue, Chun; Abadir, Peter et al. (2005) Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. Hypertension 45:133-7

Awad, Alaa S; Webb, Randy L; Carey, Robert M et al. (2005) Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. Am J Hypertens 18:544-8

Xue, Chun; Siragy, Helmy M (2005) Local renal aldosterone system and its regulation by salt, diabetes, and angiotensin II type 1 receptor. Hypertension 46:584-90