Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Modified Research Career Development Award (K04)
Project #
5K04HL003188-03
Application #
2211300
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1994-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Henry Ford Health System
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073134603
City
Detroit
State
MI
Country
United States
Zip Code
48202
LaPointe, Margot C (2005) Molecular regulation of the brain natriuretic peptide gene. Peptides 26:944-56
He, Quan; Mendez, Mariela; LaPointe, Margot C (2002) Regulation of the human brain natriuretic peptide gene by GATA-4. Am J Physiol Endocrinol Metab 283:E50-7
He, Q; Wang, D; Yang, X P et al. (2001) Inducible regulation of human brain natriuretic peptide promoter in transgenic mice. Am J Physiol Heart Circ Physiol 280:H368-76
He, Q; LaPointe, M C (2001) Src and Rac mediate endothelin-1 and lysophosphatidic acid stimulation of the human brain natriuretic peptide promoter. Hypertension 37:478-84
Schuette, R; LaPointe, M C (2000) Phorbol ester stimulates cyclooxygenase-2 expression and prostanoid production in cardiac myocytes. Am J Physiol Heart Circ Physiol 279:H719-25
Isenovic, E; LaPointe, M C (2000) Role of Ca(2+)-independent phospholipase A(2) in the regulation of inducible nitric oxide synthase in cardiac myocytes. Hypertension 35:249-54
He, Q; Wu, G; Lapointe, M C (2000) Isoproterenol and cAMP regulation of the human brain natriuretic peptide gene involves Src and Rac. Am J Physiol Endocrinol Metab 278:E1115-23
He, Q; LaPointe, M C (2000) Interleukin-1beta regulates the human brain natriuretic peptide promoter via Ca(2+)-dependent protein kinase pathways. Hypertension 35:292-6
LaPointe, M C; Isenovic, E (1999) Interleukin-1beta regulation of inducible nitric oxide synthase and cyclooxygenase-2 involves the p42/44 and p38 MAPK signaling pathways in cardiac myocytes. Hypertension 33:276-82
Wang, D; Yang, X P; Liu, Y H et al. (1999) Reduction of myocardial infarct size by inhibition of inducible nitric oxide synthase. Am J Hypertens 12:174-82

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