Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Award (K05)
Project #
5K05MH000796-08
Application #
2239999
Study Section
Neuropharmacology and Neurochemistry Review Committee (NPNC)
Project Start
1989-04-01
Project End
1999-04-30
Budget Start
1996-09-01
Budget End
1997-04-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Southern California
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Holschneider, D P; Scremin, O U; Chialvo, D R et al. (2002) Heart rate dynamics in monoamine oxidase-A- and -B-deficient mice. Am J Physiol Heart Circ Physiol 282:H1751-9
Holschneider, D P; Scremin, O U; Roos, K P et al. (2002) Increased baroreceptor response in mice deficient in monoamine oxidase A and B. Am J Physiol Heart Circ Physiol 282:H964-72
Geha, R M; Rebrin, I; Chen, K et al. (2001) Substrate and inhibitor specificities for human monoamine oxidase A and B are influenced by a single amino acid. J Biol Chem 276:9877-82
Hauptmann, N; Shih, J C (2001) 2-Naphthylamine, a compound found in cigarette smoke, decreases both monoamine oxidase A and B catalytic activity. Life Sci 68:1231-41
Wong, W K; Chen, K; Shih, J C (2001) Regulation of human monoamine oxidase B gene by Sp1 and Sp3. Mol Pharmacol 59:852-9
Rebrin, I; Geha, R M; Chen, K et al. (2001) Effects of carboxyl-terminal truncations on the activity and solubility of human monoamine oxidase B. J Biol Chem 276:29499-506
Fornai, F; Giorgi, F S; Gesi, M et al. (2001) Biochemical effects of the monoamine neurotoxins DSP-4 and MDMA in specific brain regions of MAO-B-deficient mice. Synapse 39:213-21
Holschneider, D P; Chen, K; Seif, I et al. (2001) Biochemical, behavioral, physiologic, and neurodevelopmental changes in mice deficient in monoamine oxidase A or B. Brain Res Bull 56:453-62
Geha, R M; Chen, K; Shih, J C (2000) Phe(208) and Ile(199) in human monoamine oxidase A and B do not determine substrate and inhibitor specificities as in rat. J Neurochem 75:1304-9
Holschneider, D P; Shih, J C (2000) Genotype to phenotype: challenges and opportunities. Int J Dev Neurosci 18:615-8

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