This request for an NIMH Senior Scientist Award (K05) focuses on better understanding the biopsychosocial mechanisms associated with the comorbidity of mental disorders and complex pain problems. The program addresses Goal 1 of """"""""Healthy People 2010: Understanding and Improving Health""""""""--to improve health-related quality of life, with a special focus on comorbid mental health disorders and one of the most prevalent and costly forms of pain (chronic back pain). We will also focus on successful translational intervention research, which is a high priority of NIH. My ongoing biopsychosocial research program investigating the comorbidity of mental disorders and pain contains four inter-related components: early intervention translational research; cost-effectiveness translational research; underlying neuromatrix model-related research; and fMRI research. To that end, we will pursue three separate research projects over the next five years and beyond: preventing comorbid mental disorders and physical health disability; an evaluation and early intervention study of comorbid psychiatric and temporomandibular (TMD) disorders; and a randomized trial of comorbid mental disorders and musculoskeletal pain intervention in a military population. All of these projects will focus on early detection to prevent the development of such chronic disorders, recognized as a high priority research area in the PHS Report of """"""""Healthy People 2000."""""""" Many of my current and future research projects will also evaluate a potentially heuristic theory of the interaction between pain and stress (the neuromatrix model of pain). In addition, we plan to use new fMRI technology in our future research projects to develop a more comprehensive understanding of biopsychosocial mechanisms of comorbid mental disorders and pain. This Award will enable me to maintain the momentum and clinical research advances of two previous consecutive K02 awards from NIMH.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Award (K05)
Project #
1K05MH071892-01
Application #
6816766
Study Section
Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
Program Officer
Muehrer, Peter R
Project Start
2004-09-01
Project End
2009-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
1
Fiscal Year
2004
Total Cost
$231,660
Indirect Cost
Name
University of Texas Arlington
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
064234610
City
Arlington
State
TX
Country
United States
Zip Code
76019
Brede, Emily; Mayer, Tom G; Shea, Margareta et al. (2014) Facilitating unequivocal and durable decisions in workers' compensation patients eligible for elective orthopedic surgery. J Pain 15:49-58
Asih, Sali; Neblett, Randy; Mayer, Tom G et al. (2014) Insomnia in a chronic musculoskeletal pain with disability population is independent of pain and depression. Spine J 14:2000-7
Brede, Emily; Mayer, Tom G; Worzer, Whitney E et al. (2014) Facilitating surgical decisions for patients who are uncertain: a pilot surgical option process within an interdisciplinary functional restoration program. Spine J 14:1686-93
Wilson, Hilary D; Mayer, Tom G; Gatchel, Robert J (2011) The lack of association between changes in functional outcomes and work retention in a chronic disabling occupational spinal disorder population: implications for the minimum clinical important difference. Spine (Phila Pa 1976) 36:474-80
Gatchel, Robert J; Mayer, Tom G (2010) Testing minimal clinically important difference: additional comments and scientific reality testing. Spine J 10:330-2
Whitfill, Travis; Haggard, Robbie; Bierner, Samuel M et al. (2010) Early intervention options for acute low back pain patients: a randomized clinical trial with one-year follow-up outcomes. J Occup Rehabil 20:256-63
Gatchel, Robert J; McGeary, Donald D; Peterson, Alan et al. (2009) Preliminary findings of a randomized controlled trial of an interdisciplinary military pain program. Mil Med 174:270-7
Gatchel, Robert J; Bernstein, Dana; Stowell, Anna W et al. (2008) Psychosocial differences between high-risk acute vs. chronic low back pain patients. Pain Pract 8:91-7
Gatchel, Robert J; Mayer, Tom G (2008) Evidence-informed management of chronic low back pain with functional restoration. Spine J 8:65-9
Dowling, Leah S; Gatchel, Robert J; Adams, Laura L et al. (2007) An evaluation of the predictive validity of the Pain Medication Questionnaire with a heterogeneous group of patients with chronic pain. J Opioid Manag 3:257-66

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