Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Career Awards (K06)
Project #
5K06HL003512-30
Application #
3076417
Study Section
Special Emphasis Panel (NCR)
Project Start
1977-12-01
Project End
1992-11-30
Budget Start
1991-12-15
Budget End
1992-11-30
Support Year
30
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Type
Schools of Arts and Sciences
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201
Radek, J T; Jeong, J M; Murthy, S N et al. (1993) Affinity of human erythrocyte transglutaminase for a 42-kDa gelatin-binding fragment of human plasma fibronectin. Proc Natl Acad Sci U S A 90:3152-6
Radek, J T; Jeong, J M; Wilson, J et al. (1993) Association of the A subunits of recombinant placental factor XIII with the native carrier B subunits from human plasma. Biochemistry 32:3527-34
Lorand, L; Jeong, J M; Radek, J T et al. (1993) Human plasma factor XIII: subunit interactions and activation of zymogen. Methods Enzymol 222:22-35
Lorand, L; Velasco, P T; Murthy, S N et al. (1992) Isolation of transglutaminase-reactive sequences from complex biological systems: a prominent lysine donor sequence in bovine lens. Proc Natl Acad Sci U S A 89:11161-3
LeMosy, E K; Erickson, H P; Beyer Jr, W F et al. (1992) Visualization of purified fibronectin-transglutaminase complexes. J Biol Chem 267:7880-5
Lorand, L; Parameswaran, K N; Velasco, P T et al. (1992) Biotinylated peptides containing a factor XIIIa or a tissue transglutaminase-reactive glutaminyl residue that block protein cross-linking phenomena by becoming incorporated into amine donor sites. Bioconjug Chem 3:37-41
Weraarchakul-Boonmark, N; Jeong, J M; Murthy, S N et al. (1992) Cloning and expression of chicken erythrocyte transglutaminase. Proc Natl Acad Sci U S A 89:9804-8
Lorand, L; Murthy, S N; Parameswaran, K N et al. (1992) Amide bond cleavage monitored continuously through detection of a dansylcadaverine leaving group. Biochem Biophys Res Commun 186:334-41
Wilson, J; Rickles, F R; Armstrong, P B et al. (1992) N epsilon(gamma-glutamyl)lysine crosslinks in the blood clot of the horseshoe crab, Limulus polyphemus. Biochem Biophys Res Commun 188:655-61
Murthy, S N; Wilson, J; Guy, S L et al. (1991) Intramolecular crosslinking of monomeric fibrinogen by tissue transglutaminase. Proc Natl Acad Sci U S A 88:10601-4

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