This is an application for renewal of the Geriatrics Leadership Academic Award (KO7). The overall objective is to promote aging research and education at the University of Texas Health Science Center at San Antonio by coordinating and expanding the gerontologic activities of our faculty and students. A result should be the enhancement of the quality and quantity of aging research and an increased ability of our faculty to compete for extramural funding for aging research programs from state, federal and private sources.
The specific aims are: 1. To continue the program of elective courses in gerontology for students in our Schools of Allied Health Sciences, Dentistry, Medicine, and Nursing which were initiated during the 01 year of the award. 2. To provide course work on research approaches to the study of aging for graduate students, postdoctoral trainees and faculty of basic science and clinical science departments. 3. To provide faculty and postdoctoral trainees of the clinical and basic science departments with hands-on experiences in gerontologic research including the means to conduct pilot studies. 4. To continue programs aimed at catalyzing interactions between faculty working in gerontology with research groups in our institution working in areas related to gerontology. 5. To promote the development of the recently created Aging Research and Education Center of the University of Texas Health Science Center at San Antonio. 6. To provide the Principal Investigator with training in evolutionary and comparative biology of aging and in the genetics of aging.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Academic/Teacher Award (ATA) (K07)
Project #
5K07AG000469-06
Application #
2048178
Study Section
Biological and Clinical Aging Review Committee (BCA)
Project Start
1990-04-01
Project End
1996-03-31
Budget Start
1995-04-01
Budget End
1996-03-31
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Physiology
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Klebanov, Simon; Herlihy, Jeremiah T; Freeman, Gregory L (2002) Assessing effects of long-term food restriction on myocardial energetics in the isolated heart preparation. Mech Ageing Dev 123:1375-88
Klebanov, S; Herlihy, J T (1997) Effect of life-long food restriction on cardiac myosin composition. J Gerontol A Biol Sci Med Sci 52:B184-9
Klebanov, S; Herlihy, J T; Freeman, G L (1997) Effect of long-term food restriction on cardiac mechanics. Am J Physiol 273:H2333-42
Salih, M A; Sims, S H; Kalu, D N (1996) Putative intestinal estrogen receptor: evidence for regional differences. Mol Cell Endocrinol 121:47-55
Rikke, B A; Vellanoweth, R L; Her, S et al. (1995) Cloning and sequence analysis of a novel member of the single-stranded DNA binding protein family. Biochim Biophys Acta 1261:143-6
Thomas, J; Bertrand, H; Stacy, C et al. (1993) Long-term caloric restriction improves baroreflex sensitivity in aging Fischer 344 rats. J Gerontol 48:B151-5