The overall goal of this K07 is to build a strong research and research training Pharmaceutical Outcomes Research in Aging (PORA on the strong foundation of resources at UPITT. The PORA specific aims are to: 1) create an educational series that builds a solid foundation of knowledge and skills in geriatric pharmaceutical outcomes research;2) build a cadre of well trained investigators in the field;and 3) provide experiential learning and support for data management and analysis of pharmaceutical data. In support of aim one, we will develop and provide: 1) a new 9 credit Area of Concentration in Geriatric Pharmaceutical Outcomes Research as part of the Clinical and Translational Science Institute's (CTSI) certificate, masters and PhD graduate programs;2) a credit bearing monthly geriatric pharmaceutical outcomes research seminar, 3) an annual Visiting Professorship;and 4) an annual pre-meeting workshop on Geriatric Pharmaceutical Outcomes Research at the annual Gerontological Society of America meeting. In support of aim two, I have assembled a group of senior and junior faculty mentors. Trainees will be recruited at multiple levels (junior faculty, post doctoral fellows, residents, and pre-doctoral student trainees), come from multiple disciplines including pharmacy, medicine, epidemiology, health services research and other fields and be supported through existing funding from our affiliated health care systems (UPMC and VA), the CTSI, Pepper Center and our NIA training grants. We will annually also offer a small pilot award. In support of aim three, a senior biostatistician faculty member will provide study design and statistical support for the above- mentioned trainees. An Executive Committee consisting of the PI, the biostatistician and the PI of the NIA- funded Pepper Center and T32 and T35 programs will provide administrative and intellectual leadership. The PORA will be overseen by a multidisciplinary Internal Advisory Committee to assure that the PORA is well integrated with and leverages UPITT resources including the CTSI. The candidate is a leader in the field of geriatric pharmacotherapy research and a committed teacher and mentor to beginning investigators. The long term goal of this K07 proposal is to secure a T32 and/or center/program grant to train future researchers to conduct important research to enhance the health of older adults by improving the safety and use of medications. There is strong institutional support for the PORA to assure its short and long term success.
Older patients represent a rapidly increasing segment of the population that commonly experiences medication-related problems. New investigators and additional multidisciplinary pharmaceutical outcomes research are needed to detect, better understand, prevent or reduce, medication-related problems in older adults.
|Naples, Jennifer G; Marcum, Zachary A; Perera, Subashan et al. (2016) Impact of Drug-Drug and Drug-Disease Interactions on Gait Speed in Community-Dwelling Older Adults. Drugs Aging 33:411-8|
|Tilson, Hugh; Hines, Lisa E; McEvoy, Gerald et al. (2016) Recommendations for selecting drug-drug interactions for clinical decision support. Am J Health Syst Pharm 73:576-85|
|Sevick, Mary Ann; Piraino, Beth M; St-Jules, David E et al. (2016) No Difference in Average Interdialytic Weight Gain Observed in a Randomized Trial With a Technology-Supported Behavioral Intervention to Reduce Dietary Sodium Intake in Adults Undergoing Maintenance Hemodialysis in the United States: Primary Outcomes of t J Ren Nutr 26:149-58|
|St-Jules, David E; Woolf, Kathleen; Pompeii, Mary Lou et al. (2016) Exploring Problems in Following the Hemodialysis Diet and Their Relation to Energy and Nutrient Intakes: The BalanceWise Study. J Ren Nutr 26:118-24|
|Smith, Kenneth J; Handler, Steven M; Kapoor, Wishwa N et al. (2016) Automated Communication Tools and Computer-Based Medication Reconciliation to Decrease Hospital Discharge Medication Errors. Am J Med Qual 31:315-22|
|Kane-Gill, Sandra L; Hanlon, Joseph T; Fine, Michael J et al. (2016) Physician Perceptions of Consultant Pharmacist Services Associated with an Intervention for Adverse Drug Events in the Nursing Facility. Consult Pharm 31:708-720|
|Naples, Jennifer G; Hanlon, Joseph T; Schmader, Kenneth E et al. (2016) Recent Literature on Medication Errors and Adverse Drug Events in Older Adults. J Am Geriatr Soc 64:401-8|
|Marcum, Zachary A; Perera, Subashan; Thorpe, Joshua M et al. (2016) Antidepressant Use and Recurrent Falls in Community-Dwelling Older Adults: Findings From the Health ABC Study. Ann Pharmacother 50:525-33|
|St-Jules, David E; Woolf, Kathleen; Pompeii, Mary Lou et al. (2016) Reexamining the Phosphorus-Protein Dilemma: Does Phosphorus Restriction Compromise Protein Status? J Ren Nutr 26:136-40|
|Hanlon, Joseph T; Aspinall, Sherrie L; Handler, Steven M et al. (2015) Potentially suboptimal prescribing for older veteran nursing home patients with dementia. Ann Pharmacother 49:20-8|
Showing the most recent 10 out of 106 publications