The objective of this 5-year, Mentored Clinical Scientist Development Award is to develop the skills necessary to become an independent investigator in conducting psychosocial research with alcohol using adolescents treated in Emergency Departments (EDs). Previous research has focused on the prevalence of alcohol and other substance use in relation to injury, timing of injuries, trauma recidivism, and the readiness to change in ED populations. However, the distinction between alcohol use and alcohol use disorders (AUD) in the adolescent population has been virtually ignored. Further, while preliminary efforts are now being made to establish rates of AUDs in ED populations, there is no research being done in adolescent ED populations that addresses the issue of other mental disorder symptomatology and its relationship to injury and illness. There is also a need to develop valid and reliable alcohol screening instruments that can be quickly administered to adolescents in the hectic pace of an ED environment, in order to discriminate social drinkers from actual and potential problem drinkers. Finally, the heavy use of substance and mental health rehabilitation services by adolescents, coupled with high trauma recidivism, suggests that much is being done in the attempt to help adolescents at high-risk for injury, but with little effect. A need exists to begin collecting data on what services are being used and what is effective with this population, if we are to be able to design effective interventions. Dr. Thomas Kelly has successfully coordinated psychiatric research projects at Western Psychiatric Institute and Clinic for over 10 years and has authored or co-authored six journal articles or presentations on psychiatric disorder and self-injury. He is completing a 2-year post- doctoral fellowship in an alcohol research training program at the Pittsburgh Adolescent Alcohol Research Center (PAARC), during which he became a co-investigator on an ongoing pilot study of alcohol use in ED treated adolescents. This award will permit Dr. Kelly to remain at PAARC and develop is skills in: 1) investigators the relationships between substance use and other mental disorders to injury in high-risk adolescents; 2) develop screening instruments for problematic alcohol use with this at-risk population; 3) the methodology of epidemiological research; and 4) investigating health care and social service use in adolescents treated in EDs, as a preliminary step to the design of interventions to reduce substance use and mental disorder co-morbidity in these adolescents.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08AA000280-03
Application #
6532337
Study Section
Health Services Research Review Subcommittee (AA)
Project Start
2000-09-25
Project End
2005-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
3
Fiscal Year
2002
Total Cost
$112,612
Indirect Cost
Name
University of Pittsburgh
Department
Psychiatry
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Kelly, Thomas M; Donovan, John E; Chung, Tammy et al. (2009) Brief screens for detecting alcohol use disorder among 18-20 year old young adults in emergency departments: Comparing AUDIT-C, CRAFFT, RAPS4-QF, FAST, RUFT-Cut, and DSM-IV 2-Item Scale. Addict Behav 34:668-74
Kelly, Thomas M; Donovan, John E; Cornelius, Jack R et al. (2005) Alcohol use disorder symptoms and risk-taking behavior as predictors of alcohol-related medical events among young adults treated in emergency departments. Addict Behav 30:1674-89
Cornelius, Jack R; Clark, Duncan B; Bukstein, Oscar G et al. (2005) Fluoxetine in adolescents with comorbid major depression and an alcohol use disorder: a 3-year follow-up study. Addict Behav 30:807-14
Cornelius, Jack R; Clark, Duncan B; Bukstein, Oscar G et al. (2005) Acute phase and five-year follow-up study of fluoxetine in adolescents with major depression and a comorbid substance use disorder: a review. Addict Behav 30:1824-33
Cook, Robert L; Chung, Tammy; Kelly, Thomas M et al. (2005) Alcohol screening in young persons attending a sexually transmitted disease clinic. Comparison of AUDIT, CRAFFT, and CAGE instruments. J Gen Intern Med 20:1-6
Kelly, Thomas M; Donovan, John E; Cornelius, Jack R et al. (2004) Predictors of problem drinking among older adolescent emergency department patients. J Emerg Med 27:209-18
Cornelius, Jack R; Bukstein, Oscar G; Salloum, Ihsan M et al. (2004) Fluoxetine in depressed AUD adolescents: a 1-year follow-up evaluation. J Child Adolesc Psychopharmacol 14:33-8
Cornelius, Jack R; Clark, Duncan B; Salloum, Ihsan M et al. (2004) Interventions in suicidal alcoholics. Alcohol Clin Exp Res 28:89S-96S
Kelly, Thomas M; Donovan, John E; Chung, Tammy et al. (2004) Alcohol use disorders among emergency department-treated older adolescents: a new brief screen (RUFT-Cut) using the AUDIT, CAGE, CRAFFT, and RAPS-QF. Alcohol Clin Exp Res 28:746-53
Kelly, Thomas M; Donovan, John E; Cornelius, Jack R et al. (2003) Psychiatric disorders among older adolescents treated in emergency departments on weekends: a comparison with a matched community sample. J Stud Alcohol 64:616-22

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