The primary goal of this five-year career development award is to further develop my expertise in the etiology and measurement of alcohol involvement (use and problems). To reach this immediate career goal, I will receive training in four major domains: (1) the relationship between antisocial and alcohol behavior; (2) the relationship between psychophysiology and alcohol behavior; (3) multivariate methodology for measuring alcohol involvement; and (4) the design and implementation of prospective, longitudinal investigations. The proposed training plan will include the completion of structured coursework and workshops, participation in conferences and interdisciplinary consortiums, and regular mentoring from experts in the alcohol who specialize in methodology, longitudinal research design, and the relationship of psychophysiology, antisocial behavior, and additional forms of psychopathology to alcohol problems. This training builds upon my doctoral training in methodology, my clinical training in psychopathology, and my research background on risk and protective factors for alcohol problems. Ultimately, my long-term career goal is to be a tenure track faculty member in a major research institution examining the etiology of alcohol involvement. The training plan is complemented by a research project designed to prospectively examine childhood risk factors and protective factors for alcohol involvement. Data will be collected on 35 year olds from an original sample of 1,795 participants from the island of Mauritius who have been prospectively followed since age 3 years. Three classes of childhood risk factors (psychophysiology, temperament, and behavior) and three classes of protective factors (variant alcohol metabolizing enzyme alleles, female gender, and Muslim upbringing) are hypothesized to relate to various dimensions of alcohol involvement. Four types of multivariate statistical procedures (multiple and canonical regression, structural equation modeling, and latent class analysis) will be used to assess relationships among precursors and outcome variables. The potential importance of this study regarding the etiology of alcohol problems is large and might eventually help with the development of prevention and treatment programs. This career development award will enable me to transition from an Assistant Research Professor to an independent investigator and will give me the foundation for a research career in the etiology and measurement of dimensions of alcohol involvement.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08AA014265-05
Application #
7478571
Study Section
Special Emphasis Panel (ZAA1-FF (24))
Program Officer
Shirley, Mariela
Project Start
2004-08-15
Project End
2010-07-31
Budget Start
2008-08-01
Budget End
2010-07-31
Support Year
5
Fiscal Year
2008
Total Cost
$144,923
Indirect Cost
Name
University of Southern California
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Luczak, Susan E; Liang, Tiebing; Wall, Tamara L (2017) Age of Drinking Initiation as a Risk Factor for Alcohol Use Disorder Symptoms is Moderated by ALDH2*2 and Ethnicity. Alcohol Clin Exp Res 41:1738-1744
Luczak, Susan E; Prescott, Carol A; Venables, Peter H (2017) Latent classes of alcohol problems in Mauritian men: Results from the Joint Child Health Project. Drug Alcohol Rev 36:805-812
Luczak, Susan E; Wall, Tamara L (2016) Gambling problems and comorbidity with alcohol use disorders in Chinese-, Korean-, and White-American college students. Am J Addict 25:195-202
Luczak, Susan E; Yarnell, Lisa M; Prescott, Carol A et al. (2015) Childhood cognitive measures as predictors of alcohol use and problems by mid-adulthood in a non-Western cohort. Psychol Addict Behav 29:365-70
Luczak, Susan E; Yarnell, Lisa M; Prescott, Carol A et al. (2014) Effects of ALDH2?2 on alcohol problem trajectories of Asian American college students. J Abnorm Psychol 123:130-40
Luczak, Susan E; Prescott, Carol A; Dalais, Cyril et al. (2014) Religious factors associated with alcohol involvement: results from the Mauritian Joint Child Health Project. Drug Alcohol Depend 135:37-44
Yarnell, Lisa M; Sargeant, Marsha N; Prescott, Carol A et al. (2013) Measurement invariance of internalizing and externalizing behavioral syndrome factors in a non-Western sample. Assessment 20:642-55
Luczak, Susan E; Pandika, Danielle; Shea, Shoshana H et al. (2011) ALDH2 and ADH1B interactions in retrospective reports of low-dose reactions and initial sensitivity to alcohol in Asian American college students. Alcohol Clin Exp Res 35:1238-45
Duranceaux, Nicole C E; Schuckit, Marc A; Luczak, Susan E et al. (2008) Ethnic differences in level of response to alcohol between Chinese Americans and Korean Americans. J Stud Alcohol Drugs 69:227-34
Doran, Neal; Myers, Mark G; Luczak, Susan E et al. (2007) Stability of heavy episodic drinking in Chinese- and Korean-American college students: effects of ALDH2 gene status and behavioral undercontrol. J Stud Alcohol Drugs 68:789-97

Showing the most recent 10 out of 16 publications