The incidence of falls is very high immediately after hospital discharge, yet little is known about how acute illness and hospitalization affect the risk for falls, and how falls during the post-acute period affect patient's ability to recover function and live independently. During the first half of the proposed NIA Academic Award. Dr. Mahoney will conduct a prospective study to investigate risk factors and outcomes associated with falls after hospitalization, utilizing a unique cohort of frail elderly patients recently discharged from the hospital. She will work closely with her sponsors, Dr. Mark Sager and Dr. Mari Palta in conducting this study. This research will provide Dr. Mahoney with hands-on skills in study design, data collection and data analysis, and will allow her to develop the expertise to conduct future investigations independently. This study will also provide the background and framework for development of a clinical trial, occurring in the second phase of the proposed NIA Academic Award, to improve mobility and prevent falls in the post-hospitalization period. This intervention study, which will be enhanced by close collaboration with Drs. Jim Agre and Everett Smith, will give Dr. Mahoney the opportunity to acquire skills in rehabilitation medicine and exercise physiology which will be critically important for her future investigations in the area of fall prevention.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Clinical Investigator Award (CIA) (K08)
Project #
Application #
Study Section
Biological and Clinical Aging Review Committee (BCA)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Wisconsin Madison
Other Health Professions
Schools of Medicine
United States
Zip Code
Mahoney, Jane E; Webb, Melissa J; Gray, Shelly L (2004) Zolpidem prescribing and adverse drug reactions in hospitalized general medicine patients at a Veterans Affairs hospital. Am J Geriatr Pharmacother 2:66-74
Callen, Bonnie L; Mahoney, Jane E; Grieves, Carey B et al. (2004) Frequency of hallway ambulation by hospitalized older adults on medical units of an academic hospital. Geriatr Nurs 25:212-7
Gray, S L; Mahoney, J E; Blough, D K (2001) Medication adherence in elderly patients receiving home health services following hospital discharge. Ann Pharmacother 35:539-45
Mahoney, J E; Eisner, J; Havighurst, T et al. (2000) Problems of older adults living alone after hospitalization. J Gen Intern Med 15:611-9
Gray, S L; Jenkins, M H; Mahoney, J E (2000) Psychotropic medication use in older patients referred for evaluation of falls risk. Ann Pharmacother 34:265-6
Mahoney, J E; Palta, M; Johnson, J et al. (2000) Temporal association between hospitalization and rate of falls after discharge. Arch Intern Med 160:2788-95
Gray, S L; Mahoney, J E; Blough, D K (1999) Adverse drug events in elderly patients receiving home health services following hospital discharge. Ann Pharmacother 33:1147-53
Hansen, K; Mahoney, J; Palta, M (1999) Risk factors for lack of recovery of ADL independence after hospital discharge. J Am Geriatr Soc 47:360-5
Mahoney, J E; Sager, M A; Jalaluddin, M (1999) Use of an ambulation assistive device predicts functional decline associated with hospitalization. J Gerontol A Biol Sci Med Sci 54:M83-8
Mahoney, J E (1998) Immobility and falls. Clin Geriatr Med 14:699-726

Showing the most recent 10 out of 11 publications