Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08AI001332-01A1
Application #
2057626
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Project Start
1996-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
John, Manohar; Bridges, Emily A; Miller, Andy O et al. (2002) Comparison of mucosal and systemic humoral immune responses after transcutaneous and oral immunization strategies. Vaccine 20:2720-6
Ryan, E T; Calderwood, S B (2001) Cholera vaccines. J Travel Med 8:82-91
Ryan, E T; Crean, T I; Kochi, S K et al. (2000) Development of a DeltaglnA balanced lethal plasmid system for expression of heterologous antigens by attenuated vaccine vector strains of Vibrio cholerae. Infect Immun 68:221-6
Ryan, E T; Calderwood, S B (2000) Cholera vaccines. Clin Infect Dis 31:561-5
Ryan, E T; Dhar, U; Khan, W A et al. (2000) Mortality, morbidity, and microbiology of endemic cholera among hospitalized patients in Dhaka, Bangladesh. Am J Trop Med Hyg 63:20-Dec
John, M; Crean, T I; Calderwood, S B et al. (2000) In vitro and in vivo analyses of constitutive and in vivo-induced promoters in attenuated vaccine and vector strains of Vibrio cholerae. Infect Immun 68:1171-5
Ryan, E T; Kain, K C (2000) Health advice and immunizations for travelers. N Engl J Med 342:1716-25
Ryan, E T; Crean, T I; John, M et al. (1999) In vivo expression and immunoadjuvancy of a mutant of heat-labile enterotoxin of Escherichia coli in vaccine and vector strains of Vibrio cholerae. Infect Immun 67:1694-701
Ryan, E T; Butterton, J R; Smith, R N et al. (1997) Protective immunity against Clostridium difficile toxin A induced by oral immunization with a live, attenuated Vibrio cholerae vector strain. Infect Immun 65:2941-9