Induction of Mucosal Immunity by Parenteral Inoculation

Coffin, Susan E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 1K08AI001367-01A1
• Application #: 2057672
• Study Section: Microbiology and Infectious Diseases B Subcommittee (MID)
• Project Start: 1996-08-01
• Project End: 2001-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Children's Hospital of Philadelphia
• DUNS #: 073757627
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Coffin, S E; Clark, S L (2001) Induction of intestinal rotavirus-specific antibodies in respiratory, but not gut, lymphoid tissues following mucosal immunization of mice with inactivated rotavirus. Virology 291:235-40

Coffin, S E; Clark, S L; Bos, N A et al. (1999) Migration of antigen-presenting B cells from peripheral to mucosal lymphoid tissues may induce intestinal antigen-specific IgA following parenteral immunization. J Immunol 163:3064-70

Coffin, S E; Offit, P A (1998) Induction of mucosal B-cell memory by intramuscular inoculation of mice with rotavirus. J Virol 72:3479-83

Coffin, S E; Moser, C A; Cohen, S et al. (1997) Immunologic correlates of protection against rotavirus challenge after intramuscular immunization of mice. J Virol 71:7851-6