Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08AR001770-05
Application #
3079239
Study Section
Special Emphasis Panel (ADDK)
Project Start
1987-05-01
Project End
1992-04-30
Budget Start
1991-05-01
Budget End
1992-04-30
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Hammerberg, C; Arend, W P; Fisher, G J et al. (1992) Interleukin-1 receptor antagonist in normal and psoriatic epidermis. J Clin Invest 90:571-83
Morganroth, G S; Chan, L S; Weinstein, G D et al. (1991) Proliferating cells in psoriatic dermis are comprised primarily of T cells, endothelial cells, and factor XIIIa+ perivascular dendritic cells. J Invest Dermatol 96:333-40
Hammerberg, C; Fisher, G J; Voorhees, J J et al. (1991) Elevated thymidine phosphorylase activity in psoriatic lesions accounts for the apparent presence of an epidermal ""growth inhibitor,"" but is not in itself growth inhibitory. J Invest Dermatol 97:286-90
Baadsgaard, O; Tong, P; Elder, J T et al. (1990) UM4D4+ (CDw60) T cells are compartmentalized into psoriatic skin and release lymphokines that induce a keratinocyte phenotype expressed in psoriatic lesions. J Invest Dermatol 95:275-82
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Ho, V C; Baadsgaard, O; Elder, J T et al. (1990) Genotypic analysis of T-cell clones derived from cutaneous T-cell lymphoma lesions demonstrates selective growth of tumor-infiltrating lymphocytes. J Invest Dermatol 95:4-8
Cooper, K D; Hammerberg, C; Baadsgaard, O et al. (1990) IL-1 activity is reduced in psoriatic skin. Decreased IL-1 alpha and increased nonfunctional IL-1 beta. J Immunol 144:4593-603
Ho, V C; Hansen, E R; Elder, J T et al. (1990) T cell receptor beta-chain gene rearrangement without gamma-chain gene rearrangement in cutaneous T cell lymphoma: an unusual finding. Clin Immunol Immunopathol 54:354-60
Tse, Y; Cooper, K D (1990) Cutaneous dermal Ia+ cells are capable of initiating delayed type hypersensitivity responses. J Invest Dermatol 94:267-72

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