Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08CA001100-01
Application #
3079592
Study Section
(SRC)
Project Start
1987-06-01
Project End
1990-05-31
Budget Start
1987-06-01
Budget End
1988-05-31
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92037
Carrera, C J; Piro, L D; Saven, A et al. (1991) 2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes. Adv Exp Med Biol 309A:15-8
Carrera, C J; Terai, C; Lotz, M et al. (1990) Potent toxicity of 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy. J Clin Invest 86:1480-8
Carrera, C J; Yamanaka, H; Piro, L D et al. (1989) Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo. Adv Exp Med Biol 253B:219-25
Carson, D A; Nobori, T; Kajander, E O et al. (1988) Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy. Adv Exp Med Biol 250:179-85
Piro, L D; Carrera, C J; Beutler, E et al. (1988) 2-Chlorodeoxyadenosine: an effective new agent for the treatment of chronic lymphocytic leukemia. Blood 72:1069-73