Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08DK002008-05
Application #
2133649
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1992-06-01
Project End
1997-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Iowa
Department
Pediatrics
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Murthy, S; Mathur, S; Bishop, W P et al. (1997) Inhibition of apolipoprotein B secretion by IL-6 is mediated by EGF or an EGF-like molecule in CaCo-2 cells. J Lipid Res 38:206-16
Murthy, S; Mathur, S N; Varilek, G et al. (1996) Cytokines regulate apolipoprotein B secretion by Caco-2 cells: differential effects of IL-6 and TGF-beta 1. Am J Physiol 270:G94-102
Bishop, W P; Lin, J; Stein, C A et al. (1995) Interruption of a transforming growth factor alpha autocrine loop in Caco-2 cells by antisense oligodeoxynucleotides. Gastroenterology 109:1882-9
Green, M D; Bishop, W P; Tephly, T R (1995) Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides. Drug Metab Dispos 23:299-302
Varilek, G W; Neil, G A; Bishop, W P et al. (1995) Nerve growth factor synthesis by intestinal epithelial cells. Am J Physiol 269:G445-52
Bishop, W P; Wen, J T (1994) Regulation of Caco-2 cell proliferation by basolateral membrane epidermal growth factor receptors. Am J Physiol 267:G892-900
Varilek, G W; Neil, G A; Bishop, W P (1994) Caco-2 cells express type I interleukin-1 receptors: ligand binding enhances proliferation. Am J Physiol 267:G1101-7
Mathur, S N; Born, E; Bishop, W P et al. (1993) Effect of okadaic acid on apo B and apo A-I secretion by CaCo-2 cells. Biochim Biophys Acta 1168:130-43