Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08DK002339-02
Application #
2134256
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1994-12-23
Project End
1999-11-30
Budget Start
1995-12-18
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Boushey, Robin P; Abadir, Amir; Flamez, Daisy et al. (2003) Hypoglycemia, defective islet glucagon secretion, but normal islet mass in mice with a disruption of the gastrin gene. Gastroenterology 125:1164-74
Koster, J C; Marshall, B A; Ensor, N et al. (2000) Targeted overactivity of beta cell K(ATP) channels induces profound neonatal diabetes. Cell 100:645-54
Marshall, B A; Hansen, P A; Ensor, N J et al. (1999) GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance. Am J Physiol 276:E390-400
Cheverud, J M; Pletscher, L S; Vaughn, T T et al. (1999) Differential response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains. Physiol Genomics 1:33-9
Marshall, B A; Tordjman, K; Host, H H et al. (1999) Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion. J Biol Chem 274:27426-32
Hansen, P A; Han, D H; Marshall, B A et al. (1998) A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms. J Biol Chem 273:26157-63
Scrocchi, L A; Marshall, B A; Cook, S M et al. (1998) Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling. Diabetes 47:632-9