Igfs and Skeletal Muscle Cell Differentiation

Adi, Saleh

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 1K08DK002412-01
• Application #: 2134359
• Study Section: Special Emphasis Panel (SRC)
• Project Start: 1996-07-01
• Project End: 2001-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of California San Francisco
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 073133571
• City: San Francisco
• State: CA
• Country: United States
• Zip Code: 94143

Publications

Tiffin, Nicki; Adi, Saleh; Stokoe, David et al. (2004) Akt phosphorylation is not sufficient for insulin-like growth factor-stimulated myogenin expression but must be accompanied by down-regulation of mitogen-activated protein kinase/extracellular signal-regulated kinase phosphorylation. Endocrinology 145:4991-6

Adi, Saleh; Bin-Abbas, Bassam; Wu, Nan-Yan et al. (2002) Early stimulation and late inhibition of extracellular signal-regulated kinase 1/2 phosphorylation by IGF-I: a potential mechanism mediating the switch in IGF-I action on skeletal muscle cell differentiation. Endocrinology 143:511-6

Adi, S; Wu, N Y; Rosenthal, S M (2001) Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin. Endocrinology 142:498-501

Cheng, Z Q; Adi, S; Wu, N Y et al. (2000) Functional inactivation of the IGF-I receptor delays differentiation of skeletal muscle cells. J Endocrinol 167:175-82

Adi, S; Cheng, Z Q; Zhang, P L et al. (2000) Opposing early inhibitory and late stimulatory effects of insulin-like growth factor-I on myogenin gene transcription. J Cell Biochem 78:617-26