Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08DK002446-01
Application #
2134391
Study Section
Special Emphasis Panel (SRC)
Project Start
1996-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Chang, Se-Ho; Garcia, Jairo; Melendez, J Andres et al. (2003) Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain. Biochem J 371:877-85
Hill-Kapturczak, Nathalie; Voakes, Christy; Garcia, Jairo et al. (2003) A cis-acting region regulates oxidized lipid-mediated induction of the human heme oxygenase-1 gene in endothelial cells. Arterioscler Thromb Vasc Biol 23:1416-22
Hill-Kapturczak, Nathalie; Sikorski, Eric; Voakes, Christy et al. (2003) An internal enhancer regulates heme- and cadmium-mediated induction of human heme oxygenase-1. Am J Physiol Renal Physiol 285:F515-23
Chang, Se-Ho; Barbosa-Tessmann, Ione; Chen, Chin et al. (2002) Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response. J Biol Chem 277:1933-40
Hill-Kapturczak, Nathalie; Chang, Se-Ho; Agarwal, Anupam (2002) Heme oxygenase and the kidney. DNA Cell Biol 21:307-21
Davis, C A; Nick, H S; Agarwal, A (2001) Manganese superoxide dismutase attenuates Cisplatin-induced renal injury: importance of superoxide. J Am Soc Nephrol 12:2683-90
Hill-Kapturczak, N; Thamilselvan, V; Liu, F et al. (2001) Mechanism of heme oxygenase-1 gene induction by curcumin in human renal proximal tubule cells. Am J Physiol Renal Physiol 281:F851-9
Hill-Kapturczak, N; Truong, L; Thamilselvan, V et al. (2000) Smad7-dependent regulation of heme oxygenase-1 by transforming growth factor-beta in human renal epithelial cells. J Biol Chem 275:40904-9
Shiraishi, F; Curtis, L M; Truong, L et al. (2000) Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis. Am J Physiol Renal Physiol 278:F726-36
Agarwal, A; Nick, H S (2000) Renal response to tissue injury: lessons from heme oxygenase-1 GeneAblation and expression. J Am Soc Nephrol 11:965-73

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