Abdominal pain is the single most frequent complaint for patients seen in the emergency department. The evaluation of these patients frequently involves the use of medical imaging. Computed tomography (CT) is by far the most widely used imaging modality for this indication, but exposes patients to levels of radiation that put them at risk for developing cancer. The intravenous contrast agent used for CT scans is also known to cause kidney injury, leading to dialysis and even death. Alternative imaging tests, including magnetic resonance imaging (MRI) and ultrasound (US), have high accuracy for detecting emergent causes of abdominal pain and do not expose patients to cancer-causing radiation nor kidney damaging contrast agents. Though guidelines advocating the use of US and MRI instead of CT exist, physicians are not routinely following them. This K08 proposal will evaluate the barriers and facilitators to the use of US and MRI in the emergency department. Dr. Repplinger is an Assistant Professor at the University of Wisconsin ? Madison, with a primary appointment in the BerbeeWalsh Department of Emergency Medicine and cross-appointment in the Department of Radiology. His research focuses on evaluating radiation-free imaging alternatives to CT, particularly the use of MRI. This line of investigation has been very successful due to the care he has taken in assembling and maintaining an interdisciplinary team of collaborators with expertise in medical physics, emergency care, radiology, and health services research as well as his unique qualifications. Support from this 3-year K08 award would provide Dr. Repplinger with the dedicated time needed to successfully complete his proposed research project. Further, he would be able to pursue career development activities that will significantly accelerate his progress toward becoming an independent investigator. The proposed aims are: 1) Identify high impact barriers and facilitators to guideline-adherent use of MRI and US in the ED; 2) Design a candidate intervention bundle targeted to high impact barriers and refine it using input from key stakeholders; and 3) Test the impact of the candidate intervention bundle on image test guideline adherence for pediatric appendicitis.
These aims will be accomplished using a mixed-methods approach: qualitative analysis of focus groups for aims 1 & 2 and administrative data from our electronic health record for aim 3.

Public Health Relevance

Emergency physicians very frequently use computed tomography scans in order to accurately diagnose emergency conditions, but these scans expose patients to radiation that puts them at risk for developing cancer and injuring their kidneys. Using alternative imaging tests, like magnetic resonance imaging and ultrasound, is a safer way to find the same information, and is recommended by several national guidelines. This K08 proposal will uncover why safer imaging tests are not more commonly used, which will inform future interventions aimed at improving the quality and safety of patient care in the emergency department setting.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08DK111234-01
Application #
9164245
Study Section
Digestive Diseases and Nutrition C Subcommittee (DDK-C)
Program Officer
Saslowsky, David E
Project Start
2016-09-09
Project End
2019-05-31
Budget Start
2016-09-09
Budget End
2017-05-31
Support Year
1
Fiscal Year
2016
Total Cost
$162,788
Indirect Cost
$12,058
Name
University of Wisconsin Madison
Department
Emergency Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Repplinger, Michael D; Nagle, Scott K; Harringa, John B et al. (2018) Clinical outcomes after magnetic resonance angiography (MRA) versus computed tomographic angiography (CTA) for pulmonary embolism evaluation. Emerg Radiol 25:469-477
Zhang, Albert; Yocum, Regina M; Repplinger, Michael D et al. (2018) Factors Affecting Family Presence During Fracture Reduction in the Pediatric Emergency Department. West J Emerg Med 19:970-976
Patterson, Brian W; Repplinger, Michael D; Pulia, Michael S et al. (2018) Using the Hendrich II Inpatient Fall Risk Screen to Predict Outpatient Falls After Emergency Department Visits. J Am Geriatr Soc 66:760-765
Pulia, Michael S; Schwei, Rebecca J; Patterson, Brian W et al. (2018) Effectiveness of Outpatient Antibiotics After Surgical Drainage of Abscesses in Reducing Treatment Failure. J Emerg Med 55:512-521
Repplinger, Michael D; Bracken, Rebecca L; Patterson, Brian W et al. (2018) Downstream Imaging Utilization After MR Angiography Versus CT Angiography for the Initial Evaluation of Pulmonary Embolism. J Am Coll Radiol 15:1692-1697
Harringa, John B; Bracken, Rebecca L; Nagle, Scott K et al. (2017) Negative D-dimer testing excludes pulmonary embolism in non-high risk patients in the emergency department. Emerg Radiol 24:273-280
Harringa, John B; Bracken, Rebecca L; Nagle, Scott K et al. (2017) Anemia is not a risk factor for developing pulmonary embolism. Am J Emerg Med 35:146-149
Repplinger, Michael D; Ravi, Shashank; Lee, Andrew W et al. (2017) The Impact of an Emergency Department Front-End Redesign on Patient-Reported Satisfaction Survey Results. West J Emerg Med 18:1068-1074
Patterson, Brian W; Smith, Maureen A; Repplinger, Michael D et al. (2017) Using Chief Complaint in Addition to Diagnosis Codes to Identify Falls in the Emergency Department. J Am Geriatr Soc 65:E135-E140
Kinner, Sonja; Pickhardt, Perry J; Riedesel, Erica L et al. (2017) Diagnostic Accuracy of MRI Versus CT for the Evaluation of Acute Appendicitis in Children and Young Adults. AJR Am J Roentgenol 209:911-919