Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HL001888-03
Application #
3082279
Study Section
Research Manpower Review Committee (MR)
Project Start
1986-12-01
Project End
1989-06-30
Budget Start
1988-12-01
Budget End
1989-06-30
Support Year
3
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Ring, W L; Riddick, C A; Baker, J R et al. (1997) Activated lymphocytes increase expression of 5-lipoxygenase and its activating protein in THP-1 cells. Am J Physiol 273:C2057-64
Ring, W L; Riddick, C A; Baker, J R et al. (1996) Human monocytes lose 5-lipoxygenase and FLAP as they mature into monocyte-derived macrophages in vitro. Am J Physiol 271:C372-7
Ring, W L; Riddick, C A; Baker, J R et al. (1996) Lymphocytes stimulate expression of 5-lipoxygenase and its activating protein in monocytes in vitro via granulocyte macrophage colony-stimulating factor and interleukin 3. J Clin Invest 97:1293-301
Shindo, K; Baker, J R; Munafo, D A et al. (1994) Captopril inhibits neutrophil synthesis of leukotriene B4 in vitro and in vivo. J Immunol 153:5750-9
Bigby, T D; Lee, D M; Minami, M et al. (1994) Characterization of human airway epithelial cell leukotriene A4 hydrolase. Am J Respir Cell Mol Biol 11:615-24
Munafo, D A; Shindo, K; Baker, J R et al. (1994) Leukotriene A4 hydrolase in human bronchoalveolar lavage fluid. J Clin Invest 93:1042-50
Bigby, T D (1991) Transcellular metabolism of leukotrienes in the lung. Adv Exp Med Biol 314:235-50
Bigby, T D; Lee, D M; Meslier, N et al. (1989) Leukotriene A4 hydrolase activity of human airway epithelial cells. Biochem Biophys Res Commun 164:1-7
Bigby, T D; Meslier, N (1989) Transcellular lipoxygenase metabolism between monocytes and platelets. J Immunol 143:1948-54
Tamaoki, J; Sekizawa, K; Ueki, I F et al. (1987) Effect of macrophage stimulation on parasympathetic airway contraction in dogs. Eur J Pharmacol 138:421-5