Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
1K08HL002311-01
Application #
3082683
Study Section
(SRC)
Project Start
1989-04-01
Project End
1989-08-31
Budget Start
1989-04-01
Budget End
1989-08-31
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Razdan, K; Kroll, M H (1996) Molecular cloning of a novel platelet protein showing homology to the angiotensin II receptor C-terminal domain. J Biol Chem 271:2221-4
Durante, W; Kroll, M H; Orloff, G J et al. (1996) Regulation of interleukin-1-beta-stimulated inducible nitric oxide synthase expression in cultured vascular smooth muscle cells by hemostatic proteins. Biochem Pharmacol 51:847-53
Wagner, C T; Kroll, M H; Chow, T W et al. (1996) Epinephrine and shear stress synergistically induce platelet aggregation via a mechanism that partially bypasses VWF-GP IB interactions. Biorheology 33:209-29
Kroll, M H; Hellums, J D; McIntire, L V et al. (1996) Platelets and shear stress. Blood 88:1525-41
Sullivan, R; Kunze, D L; Kroll, M H (1996) Thrombin receptors activate potassium and chloride channels. Blood 87:648-56
Kamat, S G; Michelson, A D; Benoit, S E et al. (1995) Fibrinolysis inhibits shear stress-induced platelet aggregation. Circulation 92:1399-407
Christodoulides, N; Durante, W; Kroll, M H et al. (1995) Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation 91:2306-9
Michelson, A D; Benoit, S E; Kroll, M H et al. (1994) The activation-induced decrease in the platelet surface expression of the glycoprotein Ib-IX complex is reversible. Blood 83:3562-73
Razdan, K; Hellums, J D; Kroll, M H (1994) Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s). Biochem J 302 ( Pt 3):681-6
Guo, Z; Weinstein, M J; Phillips, M D et al. (1993) M(r) 6,400 aurin tricarboxylic acid directly activates platelets. Thromb Res 71:77-88

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