Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
7K08HL002394-04
Application #
3082768
Study Section
Research Manpower Review Committee (MR)
Project Start
1989-07-01
Project End
1994-06-30
Budget Start
1991-12-15
Budget End
1992-06-30
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
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Kostyk, S K; Kourembanas, S; Wheeler, E L et al. (1995) Basic fibroblast growth factor increases nitric oxide synthase production in bovine endothelial cells. Am J Physiol 269:H1583-9
Perrella, M A; Yoshizumi, M; Fen, Z et al. (1994) Transforming growth factor-beta 1, but not dexamethasone, down-regulates nitric-oxide synthase mRNA after its induction by interleukin-1 beta in rat smooth muscle cells. J Biol Chem 269:14595-600
McQuillan, L P; Leung, G K; Marsden, P A et al. (1994) Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am J Physiol 267:H1921-7
Kourembanas, S; McQuillan, L P; Leung, G K et al. (1993) Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia. J Clin Invest 92:99-104