Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
7K08HL002505-03
Application #
3082936
Study Section
Research Manpower Review Committee (MR)
Project Start
1993-05-01
Project End
1996-08-31
Budget Start
1993-05-01
Budget End
1993-08-31
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Wilmott, R W; Kitzmiller, J A; Fiedler, M A et al. (1998) Generation of a transgenic mouse with lung-specific overexpression of the human interleukin-1 receptor antagonist protein. Am J Respir Cell Mol Biol 18:429-34
Chini, B A; Fiedler, M A; Milligan, L et al. (1998) Essential roles of NF-kappaB and C/EBP in the regulation of intercellular adhesion molecule-1 after respiratory syncytial virus infection of human respiratory epithelial cell cultures. J Virol 72:1623-6
Stark, J M; Godding, V; Sedgwick, J B et al. (1996) Respiratory syncytial virus infection enhances neutrophil and eosinophil adhesion to cultured respiratory epithelial cells. Roles of CD18 and intercellular adhesion molecule-1. J Immunol 156:4774-82
Stark, J M; Amin, R S; Trapnell, B C (1996) Infection of A549 cells with a recombinant adenovirus vector induces ICAM-1 expression and increased CD-18-dependent adhesion of activated neutrophils. Hum Gene Ther 7:1669-81
Godding, V; Stark, J M; Sedgwick, J B et al. (1995) Adhesion of activated eosinophils to respiratory epithelial cells is enhanced by tumor necrosis factor-alpha and interleukin-1 beta. Am J Respir Cell Mol Biol 13:555-62
Fiedler, M A; Wernke-Dollries, K; Stark, J M (1995) Respiratory syncytial virus increases IL-8 gene expression and protein release in A549 cells. Am J Physiol 269:L865-72
Stark, J M; van Egmond, A W; Zimmerman, J J et al. (1992) Detection of enhanced neutrophil adhesion to parainfluenza-infected airway epithelial cells using a modified myeloperoxidase assay in a microtiter format. J Virol Methods 40:225-42