Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HL002720-05
Application #
2210440
Study Section
Special Emphasis Panel (SRC (FB))
Project Start
1992-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
St. Elizabeth's Medical Center of Boston
Department
Type
DUNS #
073797292
City
Boston
State
MA
Country
United States
Zip Code
01235
Hassoun, H; Pavlovsky, M; Mansoor, S et al. (2000) Diagnosis of polycythemia vera in an anemic patient. South Med J 93:710-2
Hassoun, H; Wang, Y; Vassiliadis, J et al. (1998) Targeted inactivation of murine band 3 (AE1) gene produces a hypercoagulable state causing widespread thrombosis in vivo. Blood 92:1785-92
Hassoun, H; Hanada, T; Lutchman, M et al. (1998) Complete deficiency of glycophorin A in red blood cells from mice with targeted inactivation of the band 3 (AE1) gene. Blood 91:2146-51
Hassoun, H; Vassiliadis, J N; Murray, J et al. (1997) Characterization of the underlying molecular defect in hereditary spherocytosis associated with spectrin deficiency. Blood 90:398-406
Hassoun, H; Palek, J (1996) Hereditary spherocytosis: a review of the clinical and molecular aspects of the disease. Blood Rev 10:129-47
Hassoun, H; Vassiliadis, J N; Murray, J et al. (1996) Hereditary spherocytosis with spectrin deficiency due to an unstable truncated beta spectrin. Blood 87:2538-45
Hassoun, H; Vassiliadis, J N; Murray, J et al. (1995) Molecular basis of spectrin deficiency in beta spectrin Durham. A deletion within beta spectrin adjacent to the ankyrin-binding site precludes spectrin attachment to the membrane in hereditary spherocytosis. J Clin Invest 96:2623-9
Hassoun, H; Coetzer, T L; Vassiliadis, J N et al. (1994) A novel mobile element inserted in the alpha spectrin gene: spectrin dayton. A truncated alpha spectrin associated with hereditary elliptocytosis. J Clin Invest 94:643-8