Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HL002939-04
Application #
2210828
Study Section
Special Emphasis Panel (ZHL1-CCT-M (M2))
Project Start
1993-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Miyamoto, T; Fox, J C (2000) Autocrine signaling through Ras prevents apoptosis in vascular smooth muscle cells in vitro. J Biol Chem 275:2825-30
Miyamoto, T; Leconte, I; Swain, J L et al. (1998) Autocrine FGF signaling is required for vascular smooth muscle cell survival in vitro. J Cell Physiol 177:58-67
Neschis, D G; Safford, S D; Hanna, A K et al. (1998) Antisense basic fibroblast growth factor gene transfer reduces early intimal thickening in a rabbit femoral artery balloon injury model. J Vasc Surg 27:126-34
Kato, S; Muraishi, A; Miyamoto, T et al. (1998) Basic fibroblast growth factor regulates extracellular matrix and contractile protein expression independent of proliferation in vascular smooth muscle cells. In Vitro Cell Dev Biol Anim 34:341-6
Leconte, I; Fox, J C; Baldwin, H S et al. (1998) Adenoviral-mediated expression of antisense RNA to fibroblast growth factors disrupts murine vascular development. Dev Dyn 213:421-30
Hanna, A K; Fox, J C; Neschis, D G et al. (1997) Antisense basic fibroblast growth factor gene transfer reduces neointimal thickening after arterial injury. J Vasc Surg 25:320-5
Fox, J C; Shanley, J R (1996) Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells. J Biol Chem 271:12578-84
Kato, S; Shanley, J R; Fox, J C (1996) Serum stimulation, cell-cell interactions, and extracellular matrix independently influence smooth muscle cell phenotype in vitro. Am J Pathol 149:687-97
Fox, J C; Hsu, A Y; Swain, J L (1994) Myogenic differentiation triggered by antisense acidic fibroblast growth factor RNA. Mol Cell Biol 14:4244-50
Anumonwo, J M; Delmar, M; Jalife, J (1994) Is the ""funny"" current funnier than we thought? J Cardiovasc Electrophysiol 5:394-6