Intracellular Ph and Endothelial Mechanoreception

Ziegelstein, Roy C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Clinical Investigator Award (CIA) (K08)
• Project #: 5K08HL003102-03
• Application #: 2211112
• Study Section: Research Training Review Committee (RTR)
• Project Start: 1994-05-01
• Project End: 1999-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Johns Hopkins University
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 045911138
• City: Baltimore
• State: MD
• Country: United States
• Zip Code: 21218

Publications

Lounsbury, K M; Hu, Q; Ziegelstein, R C (2000) Calcium signaling and oxidant stress in the vasculature. Free Radic Biol Med 28:1362-9

Hu, Q; Corda, S; Zweier, J L et al. (1998) Hydrogen peroxide induces intracellular calcium oscillations in human aortic endothelial cells. Circulation 97:268-75

Hu, Q; Xia, Y; Corda, S et al. (1998) Hydrogen peroxide decreases pHi in human aortic endothelial cells by inhibiting Na+/H+ exchange. Circ Res 83:644-51

Ziegelstein, R C; Blank, P S; Cheng, L et al. (1998) Cytosolic alkalinization of vascular endothelial cells produced by an abrupt reduction in fluid shear stress. Circ Res 82:803-9