Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08HL003354-02
Application #
2027063
Study Section
Research Training Review Committee (RTR)
Project Start
1995-09-01
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Surgery
Type
Schools of Medicine
DUNS #
605799469
City
Newark
State
NJ
Country
United States
Zip Code
07107
Aramoto, Haruo; Breslin, Jerome W; Pappas, Peter J et al. (2004) Vascular endothelial growth factor stimulates differential signaling pathways in in vivo microcirculation. Am J Physiol Heart Circ Physiol 287:H1590-8
Breslin, Jerome W; Pappas, Peter J; Cerveira, Joaquim J et al. (2003) VEGF increases endothelial permeability by separate signaling pathways involving ERK-1/2 and nitric oxide. Am J Physiol Heart Circ Physiol 284:H92-H100
Varma, Shubha; Breslin, Jerome W; Lal, Brajesh K et al. (2002) p42/44MAPK regulates baseline permeability and cGMP-induced hyperpermeability in endothelial cells. Microvasc Res 63:172-8
Saito, S; Trovato, M J; You, R et al. (2001) Role of matrix metalloproteinases 1, 2, and 9 and tissue inhibitor of matrix metalloproteinase-1 in chronic venous insufficiency. J Vasc Surg 34:930-8
Lal, B K; Varma, S; Pappas, P J et al. (2001) VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways. Microvasc Res 62:252-62
Kissin, M; Kansal, N; Pappas, P J et al. (2000) Vein interposition cuffs decrease the intimal hyperplastic response of polytetrafluoroethylene bypass grafts. J Vasc Surg 31:69-83
Duran, W; Pappas, P J; Schmid-Schonbein, G W (2000) Microcirculatory inflammation in chronic venous insufficiency: current status and future directions. Microcirculation 7:S49-58
Padberg Jr, F T; Maniker, A H; Carmel, G et al. (1999) Sensory impairment: a feature of chronic venous insufficiency. J Vasc Surg 30:836-42
Pappas, P J; You, R; Rameshwar, P et al. (1999) Dermal tissue fibrosis in patients with chronic venous insufficiency is associated with increased transforming growth factor-beta1 gene expression and protein production. J Vasc Surg 30:1129-45
Curi, M A; Pappas, P J; Silva Jr, M B et al. (1999) Hemodialysis access: influence of the human immunodeficiency virus on patency and infection rates. J Vasc Surg 29:608-16

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